DNA transposon-based vectors have emerged as new potential delivery tools in therapeutic gene transfer. Such vectors are now showing promise in
DNA-dependent protein kinase (DNA-PK), which is concerned in DNA double-strand break restore and V(D)J recombination, is comprised of a DNA-targeting element termed Ku
The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.
A wide range of environmental, carcinogenic, and chemotherapeutic brokers kind bulky lesions on DNA that activate DNA damage checkpoint signaling pathways in human cells.