Tal Effectors

Transcription activator-like effectors (TALEs) acknowledge their DNA targets by way of tandem repeats, every specifying a single nucleotide base in a one-to-one sequential association. Due to this modularity and their capacity to bind lengthy DNA sequences with excessive specificity, TALEs have been utilized in many functions. Contributions of particular person repeat-nucleotide associations to affinity and specificity have been characterised.

Here, utilizing in vitro binding assays, we examined the connection between the variety of repeats in a TALE and its affinity, for each goal and non-target DNA. Each extra repeat offers additional binding power for the goal DNA, with the acquire decaying exponentially such that binding power saturates. Affinity for non-target DNA additionally will increase non-linearly with the variety of repeats, however with a slower decay of acquire.

The distinction between the impact of size on affinity for goal versus non-target DNA manifests in specificity growing then diminishing with growing TALE size, peaking between 15 and 19 repeats. Modeling throughout totally different hypothetical saturation ranges and charges of acquire decay, reflecting totally different repeat compositions, yielded a comparable vary of specificity optima. This vary encompasses the imply and median size of native TALEs, suggesting that these proteins as a group have developed for most specificity.

As a key virulence technique to trigger bacterial leaf blight, Xanthomonas oryzae pv. oryzae (Xoo) injects into the plant cell DNA-binding proteins referred to as transcription activator-like effectors (TALEs) that bind to effector-binding components (EBEs) in a sequence-specific method, leading to host gene induction. TALEs AvrXa7, PthXo3, TalC and Tal5, present in geographically distant Xoo strains, all goal OsSWEET14, thus thought of as a pivotal TALE goal performing as main susceptibility issue throughout rice-Xoo interactions.

Here, we report the technology of an allele library of the OsSWEET14 promoter via steady expression of TALE-nuclease (TALEN) constructs in rice. The susceptibility stage of traces carrying mutations in AvrXa7, Tal5 or TalC EBEs was assessed. Plants edited in AvrXa7 or Tal5 EBEs have been resistant to bacterial strains counting on the corresponding TALE. Surprisingly, though indels inside TalC EBE prevented OsSWEET14 induction in response to BAI3 wild-type micro organism counting on TalC, lack of TalC responsiveness failed to confer resistance to this pressure.

The TalC EBE mutant line was, nevertheless, resistant to a pressure expressing a synthetic SWEET14-inducing TALE whose EBE was additionally edited on this line. This work gives the primary set of alleles edited in TalC EBE and uncovers a distinct, broader vary of actions for TalC in contrast to AvrXa7 or Tal5. We suggest the existence of extra targets for TalC past SWEET14, suggesting that TALE-mediated plant susceptibility might consequence from induction of a number of, genetically redundant, host susceptibility genes by a single effector.

DNA recognition by transcription activator-like effector (TALE) proteins is mediated by tandem repeats that specify nucleotides via repeat-variable diresidues. These repeat-variable diresidues type direct and sequence-specific contacts to DNA bases; therefore, TALE-DNA interplay is delicate to DNA chemical modifications. Here we conduct a thorough investigation, overlaying all theoretical repeat-variable diresidue combos, for their recognition capabilities for 5-methylcytosine and 5-hydroxymethylcytosine, two vital epigenetic markers in greater eukaryotes.

We determine each particular and degenerate repeat-variable diresidues for 5-methylcytosine and 5-hydroxymethylcytosine. Utilizing these novel repeat-variable diresidues, we obtain methylation-dependent gene activation and genome enhancing in vivo; we additionally report base-resolution detection of 5hmC in an in vitro assay.

NEIL3 Antibody
ABD4042	Lifescience Market	100 ug	EUR 438

NEIL3 antibody
70R-18837	Fitzgerald	50 ul	EUR 435
Description: Rabbit polyclonal NEIL3 antibody

NEIL3 antibody
10R-1522	Fitzgerald	100 ug	EUR 512
Description: Mouse monoclonal NEIL3 antibody

NEIL3 Antibody
DF4042	Affbiotech	200ul	EUR 304
Description: NEIL3 Antibody detects endogenous levels of total NEIL3.

NEIL3 Antibody
1-CSB-PA003396	Cusabio	EUR 222.00 EUR 195.00	100ug 50ug
Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000

NEIL3 Antibody
CSB-PA065468-	Cusabio		EUR 335
Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

NEIL3 Antibody
CSB-PA065468-100ul	Cusabio	100ul	EUR 316
Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

NEIL3 Antibody
1-CSB-PA015695GA01HU	Cusabio	EUR 597.00 EUR 333.00	150ul 50ul
Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
DLR-NEIL3-Mu-48T	DL Develop	48T	EUR 566
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
DLR-NEIL3-Mu-96T	DL Develop	96T	EUR 741
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
RD-NEIL3-Mu-48Tests	Reddot Biotech	48 Tests	EUR 577

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
RD-NEIL3-Mu-96Tests	Reddot Biotech	96 Tests	EUR 802

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
RDR-NEIL3-Mu-48Tests	Reddot Biotech	48 Tests	EUR 603

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
RDR-NEIL3-Mu-96Tests	Reddot Biotech	96 Tests	EUR 840

Anti-NEIL3 antibody
PAab05649	Lifescience Market	100 ug	EUR 412

NEIL3 Polyclonal Antibody
ABP51918-003ml	Abbkine	0.03ml	EUR 158
Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540

NEIL3 Polyclonal Antibody
ABP51918-01ml	Abbkine	0.1ml	EUR 289
Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540

NEIL3 Polyclonal Antibody
ABP51918-02ml	Abbkine	0.2ml	EUR 414
Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540

NEIL3 Polyclonal Antibody
ES2917-100ul	ELK Biotech	100ul	EUR 279
Description: A Rabbit Polyclonal antibody against NEIL3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

NEIL3 Polyclonal Antibody
ES2917-50ul	ELK Biotech	50ul	EUR 207
Description: A Rabbit Polyclonal antibody against NEIL3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Anti-NEIL3 antibody
STJ94396	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to NEIL3.

NEIL3 Polyclonal Antibody
41212-100ul	SAB	100ul	EUR 252

NEIL3 Polyclonal Antibody
41212-50ul	SAB	50ul	EUR 187

anti- NEIL3 antibody
FNab05649	FN Test	100µg	EUR 585
Description: Antibody raised against NEIL3

NEIL3 siRNA
20-abx925706	Abbexa	EUR 551.00 EUR 732.00	15 nmol 30 nmol

NEIL3 siRNA
20-abx925707	Abbexa	EUR 551.00 EUR 732.00	15 nmol 30 nmol

NEIL3 ELISA KIT|Human
EF005329	Lifescience Market	96 Tests	EUR 689

NEIL3 Recombinant Protein (Human)
RP078087	ABM	100 ug	Ask for price

Human NEIL3 shRNA Plasmid
20-abx960591	Abbexa	EUR 801.00 EUR 1121.00	150 µg 300 µg

Anti-NEIL3/Nei3 Antibody
A05497-1	BosterBio	100ul	EUR 397
Description: Rabbit Polyclonal Antibody for NEIL3 Antibody (NEIL3) detection.tested for WB in Human, Mouse.

NEIL3 Polyclonal Conjugated Antibody
C41212	SAB	100ul	EUR 397

NEIL3 Blocking Peptide
DF4042-BP	Affbiotech	1mg	EUR 195

NEIL3 Blocking Peptide
20-abx063899	Abbexa	EUR 272.00 EUR 411.00	1 mg 5 mg

NEIL3 ORF Vector (Human) (pORF)
ORF026030	ABM	1.0 ug DNA	EUR 405

NEIL3 ELISA Kit (Human) (OKEH05107)
OKEH05107	Aviva Systems Biology	96 Wells	EUR 727
Description: Description of target: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.417 ng/mL

NEIL3 Recombinant Protein (Mouse)
RP153635	ABM	100 ug	Ask for price

NEIL3 Recombinant Protein (Rat)
RP213656	ABM	100 ug	Ask for price

Mouse NEIL3 shRNA Plasmid
20-abx982114	Abbexa	EUR 801.00 EUR 1121.00	150 µg 300 µg

NEIL3 sgRNA CRISPR Lentivector set (Human)
K1416101	ABM	3 x 1.0 ug	EUR 339

Neil3 ORF Vector (Rat) (pORF)
ORF071220	ABM	1.0 ug DNA	EUR 506

Neil3 ORF Vector (Mouse) (pORF)
ORF051213	ABM	1.0 ug DNA	EUR 506

NEIL3 ELISA Kit (Mouse) (OKCD09389)
OKCD09389	Aviva Systems Biology	96 Wells	EUR 936
Description: Description of target: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.6 Publications;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.061ng/mL

NEIL3 ELISA Kit (Mouse) (OKEH03545)
OKEH03545	Aviva Systems Biology	96 Wells	EUR 727
Description: Description of target: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.6 Publications;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.418 ng/mL

NEIL3 Protein Vector (Human) (pPB-C-His)
PV104118	ABM	500 ng	EUR 552

NEIL3 Protein Vector (Human) (pPB-N-His)
PV104119	ABM	500 ng	EUR 552

NEIL3 Protein Vector (Human) (pPM-C-HA)
PV104120	ABM	500 ng	EUR 552

NEIL3 Protein Vector (Human) (pPM-C-His)
PV104121	ABM	500 ng	EUR 552

NEIL3 sgRNA CRISPR Lentivector (Human) (Target 1)
K1416102	ABM	1.0 ug DNA	EUR 154

NEIL3 sgRNA CRISPR Lentivector (Human) (Target 2)
K1416103	ABM	1.0 ug DNA	EUR 154

NEIL3 sgRNA CRISPR Lentivector (Human) (Target 3)
K1416104	ABM	1.0 ug DNA	EUR 154

Human Endonuclease 8- like 3, NEIL3 ELISA KIT
ELI-45663h	Lifescience Market	96 Tests	EUR 824

Human NEIL3/ Endonuclease 8-like 3 ELISA Kit
E1730Hu	Sunlong	1 Kit	EUR 605

Neil3 sgRNA CRISPR Lentivector set (Rat)
K6401001	ABM	3 x 1.0 ug	EUR 339

Neil3 sgRNA CRISPR Lentivector set (Mouse)
K4227101	ABM	3 x 1.0 ug	EUR 339

Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody
20-abx129922	Abbexa	EUR 467.00 EUR 133.00 EUR 1344.00 EUR 634.00 EUR 342.00	100 ug 10 ug 1 mg 200 ug 50 ug

Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody
20-abx177722	Abbexa	EUR 1344.00 EUR 634.00	1 mg 200 ug

Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody
abx331074-100ul	Abbexa	100 ul	EUR 425

Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody
20-abx325929	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody
abx235649-100ug	Abbexa	100 ug	EUR 551

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody
20-abx008114	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody
abx030990-400ul	Abbexa	400 ul	EUR 523

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody
abx030990-80l	Abbexa	80 µl	EUR 286

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody
20-abx014459	Abbexa	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg

NEIL3 3'UTR Luciferase Stable Cell Line
TU015564	ABM	1.0 ml	EUR 1394

Neil3 3'UTR Luciferase Stable Cell Line
TU113982	ABM	1.0 ml	Ask for price

Neil3 3'UTR GFP Stable Cell Line
TU163982	ABM	1.0 ml	Ask for price

Neil3 3'UTR Luciferase Stable Cell Line
TU213880	ABM	1.0 ml	Ask for price

Neil3 3'UTR GFP Stable Cell Line
TU263880	ABM	1.0 ml	Ask for price

NEIL3 3'UTR GFP Stable Cell Line
TU065564	ABM	1.0 ml	EUR 1394

NEIL3 Protein Vector (Mouse) (pPB-C-His)
PV204850	ABM	500 ng	EUR 603

NEIL3 Protein Vector (Mouse) (pPB-N-His)
PV204851	ABM	500 ng	EUR 603

NEIL3 Protein Vector (Mouse) (pPM-C-HA)
PV204852	ABM	500 ng	EUR 603

NEIL3 Protein Vector (Mouse) (pPM-C-His)
PV204853	ABM	500 ng	EUR 603

NEIL3 Protein Vector (Rat) (pPB-C-His)
PV284878	ABM	500 ng	EUR 603

NEIL3 Protein Vector (Rat) (pPB-N-His)
PV284879	ABM	500 ng	EUR 603

NEIL3 Protein Vector (Rat) (pPM-C-HA)
PV284880	ABM	500 ng	EUR 603

NEIL3 Protein Vector (Rat) (pPM-C-His)
PV284881	ABM	500 ng	EUR 603

Neil3 sgRNA CRISPR Lentivector (Rat) (Target 1)
K6401002	ABM	1.0 ug DNA	EUR 154

Neil3 sgRNA CRISPR Lentivector (Rat) (Target 2)
K6401003	ABM	1.0 ug DNA	EUR 154

Neil3 sgRNA CRISPR Lentivector (Rat) (Target 3)
K6401004	ABM	1.0 ug DNA	EUR 154

Neil3 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K4227102	ABM	1.0 ug DNA	EUR 154

Neil3 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K4227103	ABM	1.0 ug DNA	EUR 154

Neil3 sgRNA CRISPR Lentivector (Mouse) (Target 3)
K4227104	ABM	1.0 ug DNA	EUR 154

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
K1416105	ABM	3 x 1.0 ug	EUR 376

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse)
4-PAN291Mu01	Cloud-Clone	EUR 266.00 EUR 2813.00 EUR 694.00 EUR 337.00 EUR 222.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3)

Bovine Endonuclease 8- like 3, NEIL3 ELISA KIT
ELI-23242b	Lifescience Market	96 Tests	EUR 928

Mouse Endonuclease 8- like 3, Neil3 ELISA KIT
ELI-45664m	Lifescience Market	96 Tests	EUR 865

Recombinant Nei Endonuclease VIII Like Protein 3 (NEIL3)
4-RPN291Mu01	Cloud-Clone	EUR 494.24 EUR 235.00 EUR 1578.40 EUR 592.80 EUR 1085.60 EUR 394.00 EUR 3796.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Nei Endonuclease VIII Like Protein 3 expressed in: E.coli

Mouse Neil3/ Endonuclease 8-like 3 ELISA Kit
E1017Mo	Sunlong	1 Kit	EUR 632

Mouse Neil3(Endonuclease 8-like 3) ELISA Kit
EM0777	FN Test	96T	EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.469 ng/ml

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K1416106	ABM	1.0 ug DNA	EUR 167

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
K1416107	ABM	1.0 ug DNA	EUR 167

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
K1416108	ABM	1.0 ug DNA	EUR 167

Human Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) ELISA Kit
abx520380-96tests	Abbexa	96 tests	EUR 668

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), APC
4-PAN291Mu01-APC	Cloud-Clone	EUR 374.00 EUR 3689.00 EUR 1016.00 EUR 481.00 EUR 232.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with APC.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), Biotinylated
4-PAN291Mu01-Biotin	Cloud-Clone	EUR 332.00 EUR 2763.00 EUR 803.00 EUR 411.00 EUR 228.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with Biotin.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), Cy3
4-PAN291Mu01-Cy3	Cloud-Clone	EUR 457.00 EUR 4877.00 EUR 1313.00 EUR 600.00 EUR 267.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with Cy3.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), FITC
4-PAN291Mu01-FITC	Cloud-Clone	EUR 319.00 EUR 2971.00 EUR 832.00 EUR 405.00 EUR 205.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with FITC.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), HRP
4-PAN291Mu01-HRP	Cloud-Clone	EUR 341.00 EUR 3213.00 EUR 897.00 EUR 433.00 EUR 217.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with HRP.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), PE
4-PAN291Mu01-PE	Cloud-Clone	EUR 319.00 EUR 2971.00 EUR 832.00 EUR 405.00 EUR 205.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with PE.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) Protein
20-abx167933	Abbexa	EUR 690.00 EUR 286.00 EUR 2124.00 EUR 815.00 EUR 495.00	100 ug 10 ug 1 mg 200 ug 50 ug

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), APC-Cy7
4-PAN291Mu01-APC-Cy7	Cloud-Clone	EUR 628.00 EUR 7258.00 EUR 1912.00 EUR 842.00 EUR 344.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with APC-Cy7.

NEIL3 ELISA Kit| Bovine Endonuclease 8-like 3 ELISA Kit
EF011650	Lifescience Market	96 Tests	EUR 689

Neil3 ELISA Kit| Mouse Endonuclease 8-like 3 ELISA Kit
EF013387	Lifescience Market	96 Tests	EUR 689

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
SEN291Mu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5333.64
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
SEN291Mu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 526.89
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
SEN291Mu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 709.84
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
SEN291Mu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2894.28
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
4-SEN291Mu	Cloud-Clone	EUR 5384.00 EUR 2845.00 EUR 710.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
K6401005	ABM	3 x 1.0 ug	EUR 376

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
K4227105	ABM	3 x 1.0 ug	EUR 376

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) CLIA Kit
20-abx496093	Abbexa	EUR 8569.00 EUR 4560.00 EUR 1052.00	10 × 96 tests 5 × 96 tests 96 tests

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
20-abx154440	Abbexa	EUR 7504.00 EUR 3996.00 EUR 926.00	10 × 96 tests 5 × 96 tests 96 tests

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
K6401006	ABM	1.0 ug DNA	EUR 167

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
K6401007	ABM	1.0 ug DNA	EUR 167

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
K6401008	ABM	1.0 ug DNA	EUR 167

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K4227106	ABM	1.0 ug DNA	EUR 167

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K4227107	ABM	1.0 ug DNA	EUR 167

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
K4227108	ABM	1.0 ug DNA	EUR 167

Cow Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) ELISA Kit
abx520379-96tests	Abbexa	96 tests	EUR 911

Mouse Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) ELISA Kit
abx255125-96tests	Abbexa	96 tests	EUR 668

ELISA kit for Mouse NEIL3 (Nei Endonuclease VIII Like Protein 3)
ELK8051	ELK Biotech	1 plate of 96 wells	EUR 432
Description: A sandwich ELISA kit for detection of Nei Endonuclease VIII Like Protein 3 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Human Albumin antibody
70R-7567	Fitzgerald	1 mg	EUR 140
Description: Affinity purified Goat polyclonal Human Albumin antibody

human Splunc2 Antibody
BF0019	Affbiotech	200ul	EUR 376
Description: human Splunc2 antibody detects endogenous levels of total human Splunc2.

human Albumin Antibody
BF0544	Affbiotech	200ul	EUR 376
Description: human Albumin antibody detects endogenous levels of total human Albumin.

Human P16 Antibody
BF0580	Affbiotech	200ul	EUR 376
Description: Human P16 antibody detects endogenous levels of total Human P16.

Human Albumin antibody
20C-CR2116R	Fitzgerald	1 ml	EUR 260
Description: Rabbit polyclonal Human Albumin antibody

Human RBC antibody
20R-RR003	Fitzgerald	5 mg	EUR 554
Description: Rabbit polyclonal Human RBC antibody

Human RBC antibody
20R-RR006	Fitzgerald	20 mg	EUR 327
Description: Rabbit polyclonal Human RBC antibody

Human Albumin antibody
70C-CR2116GAP	Fitzgerald	1 mg	EUR 208
Description: Affinity purified Goat polyclonal Human Albumin antibody

DPPIV (Human) Antibody
6693-50	Biovision		EUR 457

Human Macrophage antibody
10R-M102a	Fitzgerald	200 ug	EUR 575
Description: Mouse monoclonal Macrophage L1 protein Calprotectin antibody

Human TFPI Antibody
10-2815	Fitzgerald	500 ug	EUR 727
Description: Mouse anti-Human TFPI Antibody

Human IgM antibody
10-3149	Fitzgerald	1 mg	EUR 219
Description: Mouse Monoclonal Human IgM antibody

Human IgG antibody
10-3150	Fitzgerald	1 mg	EUR 208
Description: Mouse Monoclonal Human IgG antibody

Human IgA antibody
10-3151	Fitzgerald	1 mg	EUR 219
Description: Mouse Monoclonal Human IgA antibody

Human IgE antibody
10-3152	Fitzgerald	1 mg	EUR 219
Description: Mouse Monoclonal Human IgE antibody

Human Albumin antibody
20-S0103GND1-D0	Fitzgerald	10 ml	EUR 116
Description: Goat polyclonal Human Albumin antibody

Human Nuclei antibody
10R-8371	Fitzgerald	100 ul	EUR 457
Description: Mouse monoclonal Human Nuclei antibody

Human IgG antibody
10R-8446	Fitzgerald	100 ul	EUR 393
Description: Mouse monoclonal Human IgG antibody

Human IgM antibody
10R-8447	Fitzgerald	100 ul	EUR 393
Description: Mouse monoclonal Human IgM antibody

Human IgA antibody
10R-8448	Fitzgerald	100 ul	EUR 393
Description: Mouse monoclonal Human IgA antibody

Human IgA Antibody
abx234075-100ug	Abbexa	100 ug	EUR 551

Human IgA Antibody
abx234076-100ug	Abbexa	100 ug	EUR 551

Human IgG Antibody
abx234077-100ug	Abbexa	100 ug	EUR 551

Human P16 Antibody
abx011302-100ul	Abbexa	100 ul	EUR 411

Human HER2 Antibody
abx023907-100ug	Abbexa	100 ug	EUR 453

Human Merlin Antibody
abx023908-100ug	Abbexa	100 ug	EUR 453

Human CRP Antibody
abx023919-10ml	Abbexa	10 ml	EUR 356

Human IgM Antibody
abx015702-100ul	Abbexa	100 ul	EUR 411

human Splunc2 Antibody
abx015999-100ug	Abbexa	100 ug	EUR 411

Human IgA Antibody
abx019197-1mg	Abbexa	1 mg	EUR 565

Human IgG Antibody
abx019200-5mg	Abbexa	5 mg	EUR 230

Human Galanin Antibody
10871-05011	AssayPro	150 ug	EUR 217

Human Gastrin Antibody
10901-05011	AssayPro	150 ug	EUR 217

Human Ghrelin Antibody
10931-05011	AssayPro	150 ug	EUR 217

Human Angiotensinogen Antibody
11013-05011	AssayPro	150 ug	EUR 217

Human Guanylin Antibody
11021-05011	AssayPro	150 ug	EUR 217

Human Pepsinogen Antibody
11224-05011	AssayPro	150 ug	EUR 217

Human Catalase Antibody
11241-05011	AssayPro	150 ug	EUR 217

Human Haptoglobin Antibody
11371-05011	AssayPro	150 ug	EUR 217

Human Leptin Antibody
11411-05011	AssayPro	150 ug	EUR 217

Human Plasmin Antibody
11481-05011	AssayPro	150 ug	EUR 217

Human Thrombin Antibody
11571-05011	AssayPro	150 ug	EUR 217

Human GPIIbIIIa Antibody
11587-05011	AssayPro	150 ug	EUR 217

Human Thyroglobulin Antibody
11591-05011	AssayPro	150 ug	EUR 217

Human tPA Antibody
11631-05011	AssayPro	150 ug	EUR 217

Human Transferrin Antibody
11641-05011	AssayPro	150 ug	EUR 217

Human Amylin Antibody
11751-05011	AssayPro	150 ug	EUR 217

Human Albumin Antibody
12001-05011	AssayPro	150 ug	EUR 217

Human Apotransferrin Antibody
12091-05011	AssayPro	150 ug	EUR 217

Human Azurocidin Antibody
12100-05011	AssayPro	150 ug	EUR 217

Human Chylomicrons Antibody
12111-05011	AssayPro	150 ug	EUR 217

Human Hemopexin Antibody
12131-05011	AssayPro	150 ug	EUR 217

Human Recoverin Antibody
12151-05011	AssayPro	150 ug	EUR 217

Human C1QBP Antibody
13551-05011	AssayPro	150 ug	EUR 217

Human Apolactoferrin Antibody
14080-05011	AssayPro	150 ug	EUR 217

Our work deciphers repeat-variable diresidues for 5-methylcytosine and 5-hydroxymethylcytosine, and offers instruments for TALE-dependent epigenome recognition.Transcription activator-like effector proteins recognise particular DNA sequences by way of tandem repeats. Here the authors show TALEs can recognise the methylated bases 5mC and 5hmC, enabling them to detect epigenetic modifications.