Sunday, 03 March, 2024

Tal Effectors

Transcription activator-like effector nuclease

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  • daTALbase: a database for genomic and transcriptomic data related to TAL effectors.
daTALbase: a database for genomic and transcriptomic data related to TAL effectors.
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daTALbase: a database for genomic and transcriptomic data related to TAL effectors.

Transcription activator-like effectors (TALEs) are proteins discovered within the genus Xanthomonas of phytopathogenic micro organism. These proteins enter the nucleus of cells within the host plant and can induce the expression of susceptibility genes (S genes), triggering illness. TALEs bind the promoter area of S genes following a particular code, which permits the prediction of binding websites based mostly on TALEs amino acid sequences.
New candidate S genes can then be found by discovering the intersection between genes induced within the presence of TALEs and genes containing predicted effector binding components. By contrasting differential expression data and binding website predictions throughout totally different datasets, patterns of TALE diversification or convergence could also be unveiled, however this requires the seamless integration of various genomic and transcriptomic data.
With this in thoughts, we current daTALbase, a curated relational database that integrates TALE-related data together with bacterial TALE sequences, plant promoter sequences, predicted TALE binding websites, transcriptomic data of host crops in response to TALE-harboring micro organism, and different related data. The database might be explored to uncover new candidate S genes in addition to to research variation in TALE repertories and their corresponding targets. The first model of the database right here offered consists of data for Oryza sp.-Xanthomonas pv. oryzae interactions. Future variations of the database will incorporate info for different pathosystems involving TALEs.

The impact of accelerating numbers of repeats on TAL effector DNA binding specificity.

Transcription activator-like effectors (TALEs) acknowledge their DNA targets by way of tandem repeats, every specifying a single nucleotide base in a one-to-one sequential association. Due to this modularity and their capacity to bind lengthy DNA sequences with excessive specificity, TALEs have been utilized in many functions. Contributions of particular person repeat-nucleotide associations to affinity and specificity have been characterised.
Here, utilizing in vitro binding assays, we examined the connection between the variety of repeats in a TALE and its affinity, for each goal and non-target DNA. Each extra repeat offers additional binding power for the goal DNA, with the acquire decaying exponentially such that binding power saturates. Affinity for non-target DNA additionally will increase non-linearly with the variety of repeats, however with a slower decay of acquire.
The distinction between the impact of size on affinity for goal versus non-target DNA manifests in specificity growing then diminishing with growing TALE size, peaking between 15 and 19 repeats. Modeling throughout totally different hypothetical saturation ranges and charges of acquire decay, reflecting totally different repeat compositions, yielded a comparable vary of specificity optima. This vary encompasses the imply and median size of native TALEs, suggesting that these proteins as a group have developed for most specificity.

Targeted promoter enhancing for rice resistance to Xanthomonas oryzae pv. oryzae reveals differential actions for SWEET14-inducing TAL effectors.

As a key virulence technique to trigger bacterial leaf blight, Xanthomonas oryzae pv. oryzae (Xoo) injects into the plant cell DNA-binding proteins referred to as transcription activator-like effectors (TALEs) that bind to effector-binding components (EBEs) in a sequence-specific method, leading to host gene induction. TALEs AvrXa7, PthXo3, TalC and Tal5, present in geographically distant Xoo strains, all goal OsSWEET14, thus thought of as a pivotal TALE goal performing as main susceptibility issue throughout rice-Xoo interactions.
Here, we report the technology of an allele library of the OsSWEET14 promoter via steady expression of TALE-nuclease (TALEN) constructs in rice. The susceptibility stage of traces carrying mutations in AvrXa7, Tal5 or TalC EBEs was assessed. Plants edited in AvrXa7 or Tal5 EBEs have been resistant to bacterial strains counting on the corresponding TALE. Surprisingly, though indels inside TalC EBE prevented OsSWEET14 induction in response to BAI3 wild-type micro organism counting on TalC, lack of TalC responsiveness failed to confer resistance to this pressure.
The TalC EBE mutant line was, nevertheless, resistant to a pressure expressing a synthetic SWEET14-inducing TALE whose EBE was additionally edited on this line. This work gives the primary set of alleles edited in TalC EBE and uncovers a distinct, broader vary of actions for TalC in contrast to AvrXa7 or Tal5. We suggest the existence of extra targets for TalC past SWEET14, suggesting that TALE-mediated plant susceptibility might consequence from induction of a number of, genetically redundant, host susceptibility genes by a single effector.

Deciphering TAL effectors for 5-methylcytosine and 5-hydroxymethylcytosine recognition.

DNA recognition by transcription activator-like effector (TALE) proteins is mediated by tandem repeats that specify nucleotides via repeat-variable diresidues. These repeat-variable diresidues type direct and sequence-specific contacts to DNA bases; therefore, TALE-DNA interplay is delicate to DNA chemical modifications. Here we conduct a thorough investigation, overlaying all theoretical repeat-variable diresidue combos, for their recognition capabilities for 5-methylcytosine and 5-hydroxymethylcytosine, two vital epigenetic markers in greater eukaryotes.
daTALbase: a database for genomic and transcriptomic data related to TAL effectors.
We determine each particular and degenerate repeat-variable diresidues for 5-methylcytosine and 5-hydroxymethylcytosine. Utilizing these novel repeat-variable diresidues, we obtain methylation-dependent gene activation and genome enhancing in vivo; we additionally report base-resolution detection of 5hmC in an in vitro assay.

NEIL3 Antibody

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NEIL3 antibody

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Description: Rabbit polyclonal NEIL3 antibody

NEIL3 antibody

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Description: Rabbit Polyclonal NEIL3 antibody

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Description: Purified Polyclonal NEIL3 antibody

NEIL3 Antibody

1-CSB-PA003396 Cusabio
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Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000

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Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

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CSB-PA065468-100ul Cusabio 100ul 379.2 EUR
Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

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Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540

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Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540

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ABP51918-02ml Abbkine 0.2ml 496.8 EUR
Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540

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NEIL3 Polyclonal Antibody

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NEIL3 Polyclonal Antibody

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Description: A Rabbit Polyclonal antibody against NEIL3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

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Description: A Rabbit Polyclonal antibody against NEIL3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

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NEIL3(Center) Rabbit Polyclonal Antibody

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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

NEIL3 ELISA KIT|Human

EF005329 Lifescience Market 96 Tests 826.8 EUR

Human NEIL3 shRNA Plasmid

20-abx960591 Abbexa
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ARP75647_P050-25UL - NEIL3 Antibody - middle region

ARP75647_P050-25UL Aviva Systems Biology 25ul 99 EUR

ARP75647_P050 - NEIL3 Antibody - middle region (ARP75647_P050)

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NEIL3 Recombinant Protein (Human)

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NEIL3 (GFP-tagged) - Human nei endonuclease VIII-like 3 (E. coli) (NEIL3)

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OASG04892-100UL - NEIL3 Antibody - C-terminal region

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Human NEIL3 knockout cell line

ABC-KH10006 AcceGen 1 vial Ask for price
Description: Human NEIL3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

NEIL3 ORF Vector (Human) (pORF)

ORF026030 ABM 1.0 ug DNA 486 EUR

Human NEIL3 knockdown cell line

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Description: Human NEIL3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human NEIL3 Protein Lysate 20ug

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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody

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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody

20-abx177722 Abbexa
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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody

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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody

abx331074-100ul Abbexa 100 ul 510 EUR

Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody

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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody

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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody

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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody

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NEI3 (NEIL3) (164-177) rabbit polyclonal antibody, Aff - Purified

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NEIL3 ELISA Kit (Human) (OKEH05107)

OKEH05107 Aviva Systems Biology 96 Wells 872.4 EUR
Description: Description of target: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.417 ng/mL

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Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody

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Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody

abx030990-400ul Abbexa 400 ul 627.6 EUR

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody

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20-abx014459 Abbexa
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Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody

abx235649-100ug Abbexa 100 ug 661.2 EUR

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody

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NEIL3 siRNA

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NEIL3 siRNA

20-abx925707 Abbexa
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OKEH05107-96W - NEIL3 ELISA Kit (Human)

OKEH05107-96W Aviva Systems Biology 96Wells 600 EUR

NEIL3 sgRNA CRISPR Lentivector set (Human)

K1416101 ABM 3 x 1.0 ug 406.8 EUR

NEIL3 Protein Vector (Human) (pPM-C-HA)

PV104120 ABM 500 ng 662.4 EUR

NEIL3 Protein Vector (Human) (pPB-C-His)

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NEIL3 Protein Vector (Human) (pPB-N-His)

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NEIL3 Protein Vector (Human) (pPM-C-His)

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Neil3 (GFP-tagged) - Mouse nei like 3 (E. coli) (Neil3)

MG209359 Origene Technologies GmbH 10 µg Ask for price

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody

CAU21269-100ul Biomatik Corporation 100ul 265.9 EUR

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody

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Human NEIL3 Over-expressing Stable Cell Line

ABC-X2020 AcceGen 1 vial Ask for price
Description: Gentaur can provide custom lentiviral constructs expressing any genes of interest as long as it is less than about 3 kb. Lentiviral technology enables us to efficiently generate stable expression lines which are then selected for moderate or high expressers, depending on the experimental requirements. If you are interested in specific lentiviral DNA constructs or have further questions, please contact us to discuss the details. NEIL3 nei endonuclease VIII-like 3 (E. coli) [ Homo sapiens ] http://www.ncbi.nlm.nih.gov/gene/55247

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NEIL3 sgRNA CRISPR Lentivector (Human) (Target 1)

K1416102 ABM 1.0 ug DNA 184.8 EUR

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NEIL3 Blocking Peptide

20-abx063899 Abbexa
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NEIL3 Blocking Peptide

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Human NEIL3/ Endonuclease 8-like 3 ELISA Kit

E1730Hu Sunlong 1 Kit 515 EUR
Description: DNA glycosylase FPG2,DNA glycosylase/AP lyase Neil3,Endonuclease VIII-like 3,Nei-like protein 3

Human NEIL3 / Endonuclease 8-like 3 ELISA Kit

E4282h EIAab 96T 736 EUR

Lenti ORF particles, NEIL3 (mGFP-tagged) - Human nei endonuclease VIII-like 3 (E. coli) (NEIL3), 200ul, >10^7 TU/mL

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Polyclonal Antibody to Nei Endonuclease VIII Like Protein 3 (NEIL3)

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Neil3 (Myc-DDK-tagged) - Mouse nei like 3 (E. coli) (Neil3)

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Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse)

4-PAN291Mu01 Cloud-Clone
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Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3)

Human Endonuclease 8-like 3 (NEIL3) ELISA Kit

RK11648 Abclonal 96T 280 EUR

Lenti ORF particles, NEIL3 (Myc-DDK tagged) - Human nei endonuclease VIII-like 3 (E. coli) (NEIL3), 200ul, >10^7 TU/mL

RC206838L1V Origene Technologies GmbH 200 µl Ask for price

Lenti ORF particles, NEIL3 (Myc-DDK tagged) - Human nei endonuclease VIII-like 3 (E. coli) (NEIL3), 200ul, >10^7 TU/mL

RC206838L3V Origene Technologies GmbH 200 µl Ask for price

Neil3 (untagged) - Rat nei endonuclease VIII-like 3 (E. coli) (Neil3)

RN216990 Origene Technologies GmbH 10 µg Ask for price

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), APC

4-PAN291Mu01-APC Cloud-Clone
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Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with APC.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), Cy3

4-PAN291Mu01-Cy3 Cloud-Clone
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Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with Cy3.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), HRP

4-PAN291Mu01-HRP Cloud-Clone
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Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with HRP.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), PE

4-PAN291Mu01-PE Cloud-Clone
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Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with PE.

NEIL3 (Center) Rabbit pAb

E2618704 EnoGene 100ul 225 EUR
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Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), FITC

4-PAN291Mu01-FITC Cloud-Clone
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Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with FITC.

Mouse NEIL3 shRNA Plasmid

20-abx982114 Abbexa
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NEIL3 Recombinant Protein (Rat)

RP213656 ABM 100 ug Ask for price

NEIL3 Recombinant Protein (Mouse)

RP153635 ABM 100 ug Ask for price

Neil3 (myc-DDK-tagged) - Rat nei endonuclease VIII-like 3 (E. coli) (Neil3)

RR216990 Origene Technologies GmbH 10 µg Ask for price

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), Biotinylated

4-PAN291Mu01-Biotin Cloud-Clone
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Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with Biotin.

Lenti ORF clone of Neil3 (mGFP-tagged) - Mouse nei like 3 (E. coli) (Neil3)

MR209359L4 Origene Technologies GmbH 10 µg Ask for price

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), APC-Cy7

4-PAN291Mu01-APC-Cy7 Cloud-Clone
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Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with APC-Cy7.

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

DLR-NEIL3-Hu DL Develop 96T 505 EUR
Description: tissue homogenates, cell lysates or other biological fluids.

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

DLR-NEIL3-Hu-48T DL Develop 48T 664.8 EUR
Description: A sandwich quantitative ELISA assay kit for detection of Human Nei Endonuclease VIII Like Protein 3 (NEIL3) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

DLR-NEIL3-Hu-96T DL Develop 96T 870 EUR
Description: A sandwich quantitative ELISA assay kit for detection of Human Nei Endonuclease VIII Like Protein 3 (NEIL3) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

DL-NEIL3-Hu DL Develop 96T 481 EUR
Description: tissue homogenates, cell lysates or other biological fluids.

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

EK17496 SAB 96Т 768 EUR

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

RDR-NEIL3-Hu-48T Reddot Biotech 48T 518.18 EUR
Description: tissue homogenates, cell lysates and other biological fluids.

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

RDR-NEIL3-Hu-48Tests Reddot Biotech 48 Tests 706.8 EUR

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

RDR-NEIL3-Hu-96T Reddot Biotech 96T 740.25 EUR
Description: tissue homogenates, cell lysates and other biological fluids.

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

RDR-NEIL3-Hu-96Tests Reddot Biotech 96 Tests 984 EUR

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

RD-NEIL3-Hu-48T Reddot Biotech 48T 493.5 EUR
Description: tissue homogenates, cell lysates and other biological fluids.

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

RD-NEIL3-Hu-48Tests Reddot Biotech 48 Tests 675.6 EUR

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

RD-NEIL3-Hu-96T Reddot Biotech 96T 705 EUR
Description: tissue homogenates, cell lysates and other biological fluids.

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit

RD-NEIL3-Hu-96Tests Reddot Biotech 96 Tests 939.6 EUR

Neil3 ORF Vector (Rat) (pORF)

ORF071220 ABM 1.0 ug DNA 607.2 EUR

NEIL3 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR324399 Origene Technologies GmbH 2 nmol Ask for price

Neil3 ORF Vector (Mouse) (pORF)

ORF051213 ABM 1.0 ug DNA 607.2 EUR

Lenti ORF clone of Neil3 (Myc-DDK-tagged) - Mouse nei like 3 (E. coli) (Neil3)

MR209359L3 Origene Technologies GmbH 10 µg Ask for price

Human Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) ELISA Kit

abx520380-96tests Abbexa 96 tests 801.6 EUR

NEIL3 ELISA Kit (Mouse) (OKEH03545)

OKEH03545 Aviva Systems Biology 96 Wells 872.4 EUR
Description: Description of target: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.6 Publications;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.418 ng/mL

NEIL3 ELISA Kit (Mouse) (OKCD09389)

OKCD09389 Aviva Systems Biology 96 Wells 1123.2 EUR
Description: Description of target: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.6 Publications;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.061ng/mL

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K1416105 ABM 3 x 1.0 ug 451.2 EUR

OCOA09652-20UG - NEIL3 Protein Lysate

OCOA09652-20UG Aviva Systems Biology 20ug 169 EUR

NEIL3 Over-expression Lysate Product

GWB-F90B65 GenWay Biotech 0.1 mg Ask for price

Lenti ORF particles, Neil3 (GFP-tagged) - Mouse nei like 3 (E. coli) (Neil3), 200ul, >10^7 TU/mL

MR209359L4V Origene Technologies GmbH 200 µl Ask for price

OPCD05616-10UG - NEIL3 Recombinant Protein

OPCD05616-10UG Aviva Systems Biology 10ug 139 EUR

OPCD05616-50UG - NEIL3 Recombinant Protein

OPCD05616-50UG Aviva Systems Biology 50ug 349 EUR

OPCD05616-200UG - NEIL3 Recombinant Protein

OPCD05616-200UG Aviva Systems Biology 200ug 689 EUR

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K1416106 ABM 1.0 ug DNA 200.4 EUR

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K1416107 ABM 1.0 ug DNA 200.4 EUR

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K1416108 ABM 1.0 ug DNA 200.4 EUR

OKEH03545-96W - NEIL3 ELISA Kit (Mouse)

OKEH03545-96W Aviva Systems Biology 96Wells 600 EUR

OKCD09389-96W - NEIL3 ELISA Kit (Mouse)

OKCD09389-96W Aviva Systems Biology 96Wells 750 EUR

Lenti ORF particles, Neil3 (Myc-DDK-tagged) - Mouse nei like 3 (E. coli) (Neil3), 200ul, >10^7 TU/mL

MR209359L3V Origene Technologies GmbH 200 µl Ask for price

NEIL3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector

TL302985 Origene Technologies GmbH 5 µg/vial Ask for price

Neil3 sgRNA CRISPR Lentivector set (Rat)

K6401001 ABM 3 x 1.0 ug 406.8 EUR

Neil3 sgRNA CRISPR Lentivector set (Mouse)

K4227101 ABM 3 x 1.0 ug 406.8 EUR

NEIL3 3'UTR GFP Stable Cell Line

TU065564 ABM 1.0 ml 1672.8 EUR

Neil3 3'UTR GFP Stable Cell Line

TU163982 ABM 1.0 ml Ask for price

Neil3 3'UTR GFP Stable Cell Line

TU263880 ABM 1.0 ml Ask for price

NEIL3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector

TR302985 Origene Technologies GmbH 5 µg/vial Ask for price

AAP75647-100UG - NEIL3 Peptide - middle region

AAP75647-100UG Aviva Systems Biology 100ug 99 EUR

NEIL3 Protein Vector (Rat) (pPM-C-HA)

PV284880 ABM 500 ng 723.6 EUR

NEIL3 Protein Vector (Rat) (pPB-C-His)

PV284878 ABM 500 ng 723.6 EUR

NEIL3 Protein Vector (Rat) (pPB-N-His)

PV284879 ABM 500 ng 723.6 EUR

NEIL3 Protein Vector (Rat) (pPM-C-His)

PV284881 ABM 500 ng 723.6 EUR

NEIL3 Protein Vector (Mouse) (pPM-C-HA)

PV204852 ABM 500 ng 723.6 EUR

NEIL3 Protein Vector (Mouse) (pPB-C-His)

PV204850 ABM 500 ng 723.6 EUR

NEIL3 Protein Vector (Mouse) (pPB-N-His)

PV204851 ABM 500 ng 723.6 EUR

NEIL3 Protein Vector (Mouse) (pPM-C-His)

PV204853 ABM 500 ng 723.6 EUR

NEIL3 3'UTR Luciferase Stable Cell Line

TU015564 ABM 1.0 ml 1672.8 EUR

Neil3 3'UTR Luciferase Stable Cell Line

TU113982 ABM 1.0 ml Ask for price

Neil3 3'UTR Luciferase Stable Cell Line

TU213880 ABM 1.0 ml Ask for price

Neil3 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6401002 ABM 1.0 ug DNA 184.8 EUR

Neil3 sgRNA CRISPR Lentivector (Rat) (Target 2)

K6401003 ABM 1.0 ug DNA 184.8 EUR

Neil3 sgRNA CRISPR Lentivector (Rat) (Target 3)

K6401004 ABM 1.0 ug DNA 184.8 EUR

Neil3 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4227102 ABM 1.0 ug DNA 184.8 EUR

Neil3 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4227103 ABM 1.0 ug DNA 184.8 EUR

Neil3 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4227104 ABM 1.0 ug DNA 184.8 EUR

Lenti ORF clone of Human nei endonuclease VIII-like 3 (E. coli) (NEIL3), mGFP tagged

RC206838L2 Origene Technologies GmbH 10 µg Ask for price

Lenti ORF clone of Human nei endonuclease VIII-like 3 (E. coli) (NEIL3), mGFP tagged

RC206838L4 Origene Technologies GmbH 10 µg Ask for price

Mouse Endonuclease 8- like 3, Neil3 ELISA KIT

ELI-45664m Lifescience Market 96 Tests 1038 EUR

Mouse Neil3/ Endonuclease 8-like 3 ELISA Kit

E1017Mo Sunlong 1 Kit 543 EUR
Description: DNA glycosylase FPG2,DNA glycosylase/AP lyase Neil3,Endonuclease VIII-like 3,Nei-like protein 3

Mouse Endonuclease 8-like 3(NEIL3) Elisa kit

EK731340 AFG Bioscience LLC 96 Wells 0.77 EUR

Bovine Endonuclease 8- like 3, NEIL3 ELISA KIT

ELI-23242b Lifescience Market 96 Tests 1113.6 EUR

Mouse Neil3(Endonuclease 8-like 3) ELISA Kit

EM0777 FN Test 96T 628.92 EUR
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.469 ng/ml

Mouse Endonuclease 8-like 3 (NEIL3) ELISA Kit

RK13400 Abclonal 96T 280 EUR

Mouse Neil3 / Endonuclease 8-like 3 ELISA Kit

E4282m EIAab 96T 776 EUR

Bovine NEIL3 / Endonuclease 8-like 3 ELISA Kit

E4282b EIAab 96T 900 EUR

Mouse Endonuclease 8 Like 3, NEIL3 GENLISA ELISA

KLM2049 Krishgen 1 x 96 wells 341 EUR

Recombinant Nei Endonuclease VIII Like Protein 3 (NEIL3)

RPU57734-100ug Biomatik Corporation 100ug 470.4 EUR

Recombinant Nei Endonuclease VIII Like Protein 3 (NEIL3)

RPU57734-1mg Biomatik Corporation 1mg 2184 EUR

Recombinant Nei Endonuclease VIII Like Protein 3 (NEIL3)

RPU57734-50ug Biomatik Corporation 50ug 385 EUR

Recombinant Nei Endonuclease VIII Like Protein 3 (NEIL3)

RPN291Mu01 Cloud-Clone 10ug 176 EUR

Recombinant Nei Endonuclease VIII Like Protein 3 (NEIL3)

4-RPN291Mu01 Cloud-Clone
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  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Nei Endonuclease VIII Like Protein 3 expressed in: E.coli

Recombinant Nei Endonuclease VIII Like Protein 3 (NEIL3)

RPU53294-100ug Biomatik Corporation 100ug 542.3 EUR
Our work deciphers repeat-variable diresidues for 5-methylcytosine and 5-hydroxymethylcytosine, and offers instruments for TALE-dependent epigenome recognition.Transcription activator-like effector proteins recognise particular DNA sequences by way of tandem repeats. Here the authors show TALEs can recognise the methylated bases 5mC and 5hmC, enabling them to detect epigenetic modifications.

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