Tal Effectors

Transcription activator-like effector nuclease

daTALbase: a database for genomic and transcriptomic data related to TAL effectors.

Posted on by Kaitlyn
daTALbase: a database for genomic and transcriptomic data related to TAL effectors.
Transcription activator-like effectors (TALEs) are proteins discovered within the genus Xanthomonas of phytopathogenic micro organism. These proteins enter the nucleus of cells within the host plant and can induce the expression of susceptibility genes (S genes), triggering illness. TALEs bind the promoter area of S genes following a particular code, which permits the prediction of binding websites based mostly on TALEs amino acid sequences.
New candidate S genes can then be found by discovering the intersection between genes induced within the presence of TALEs and genes containing predicted effector binding components. By contrasting differential expression data and binding website predictions throughout totally different datasets, patterns of TALE diversification or convergence could also be unveiled, however this requires the seamless integration of various genomic and transcriptomic data.
With this in thoughts, we current daTALbase, a curated relational database that integrates TALE-related data together with bacterial TALE sequences, plant promoter sequences, predicted TALE binding websites, transcriptomic data of host crops in response to TALE-harboring micro organism, and different related data. The database might be explored to uncover new candidate S genes in addition to to research variation in TALE repertories and their corresponding targets. The first model of the database right here offered consists of data for Oryza sp.-Xanthomonas pv. oryzae interactions. Future variations of the database will incorporate info for different pathosystems involving TALEs.

The impact of accelerating numbers of repeats on TAL effector DNA binding specificity.

Transcription activator-like effectors (TALEs) acknowledge their DNA targets by way of tandem repeats, every specifying a single nucleotide base in a one-to-one sequential association. Due to this modularity and their capacity to bind lengthy DNA sequences with excessive specificity, TALEs have been utilized in many functions. Contributions of particular person repeat-nucleotide associations to affinity and specificity have been characterised.
Here, utilizing in vitro binding assays, we examined the connection between the variety of repeats in a TALE and its affinity, for each goal and non-target DNA. Each extra repeat offers additional binding power for the goal DNA, with the acquire decaying exponentially such that binding power saturates. Affinity for non-target DNA additionally will increase non-linearly with the variety of repeats, however with a slower decay of acquire.
The distinction between the impact of size on affinity for goal versus non-target DNA manifests in specificity growing then diminishing with growing TALE size, peaking between 15 and 19 repeats. Modeling throughout totally different hypothetical saturation ranges and charges of acquire decay, reflecting totally different repeat compositions, yielded a comparable vary of specificity optima. This vary encompasses the imply and median size of native TALEs, suggesting that these proteins as a group have developed for most specificity.

Targeted promoter enhancing for rice resistance to Xanthomonas oryzae pv. oryzae reveals differential actions for SWEET14-inducing TAL effectors.

As a key virulence technique to trigger bacterial leaf blight, Xanthomonas oryzae pv. oryzae (Xoo) injects into the plant cell DNA-binding proteins referred to as transcription activator-like effectors (TALEs) that bind to effector-binding components (EBEs) in a sequence-specific method, leading to host gene induction. TALEs AvrXa7, PthXo3, TalC and Tal5, present in geographically distant Xoo strains, all goal OsSWEET14, thus thought of as a pivotal TALE goal performing as main susceptibility issue throughout rice-Xoo interactions.
Here, we report the technology of an allele library of the OsSWEET14 promoter via steady expression of TALE-nuclease (TALEN) constructs in rice. The susceptibility stage of traces carrying mutations in AvrXa7, Tal5 or TalC EBEs was assessed. Plants edited in AvrXa7 or Tal5 EBEs have been resistant to bacterial strains counting on the corresponding TALE. Surprisingly, though indels inside TalC EBE prevented OsSWEET14 induction in response to BAI3 wild-type micro organism counting on TalC, lack of TalC responsiveness failed to confer resistance to this pressure.
The TalC EBE mutant line was, nevertheless, resistant to a pressure expressing a synthetic SWEET14-inducing TALE whose EBE was additionally edited on this line. This work gives the primary set of alleles edited in TalC EBE and uncovers a distinct, broader vary of actions for TalC in contrast to AvrXa7 or Tal5. We suggest the existence of extra targets for TalC past SWEET14, suggesting that TALE-mediated plant susceptibility might consequence from induction of a number of, genetically redundant, host susceptibility genes by a single effector.

Deciphering TAL effectors for 5-methylcytosine and 5-hydroxymethylcytosine recognition.

DNA recognition by transcription activator-like effector (TALE) proteins is mediated by tandem repeats that specify nucleotides via repeat-variable diresidues. These repeat-variable diresidues type direct and sequence-specific contacts to DNA bases; therefore, TALE-DNA interplay is delicate to DNA chemical modifications. Here we conduct a thorough investigation, overlaying all theoretical repeat-variable diresidue combos, for their recognition capabilities for 5-methylcytosine and 5-hydroxymethylcytosine, two vital epigenetic markers in greater eukaryotes.
daTALbase: a database for genomic and transcriptomic data related to TAL effectors.
We determine each particular and degenerate repeat-variable diresidues for 5-methylcytosine and 5-hydroxymethylcytosine. Utilizing these novel repeat-variable diresidues, we obtain methylation-dependent gene activation and genome enhancing in vivo; we additionally report base-resolution detection of 5hmC in an in vitro assay.

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
RDR-NEIL3-Hu-48Tests 48 Tests
EUR 589

Human Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
RDR-NEIL3-Hu-96Tests 96 Tests
EUR 820

NEIL3 antibody
70R-51024 100 ul
EUR 244
Description: Purified Polyclonal NEIL3 antibody

NEIL3 antibody
70R-36850 100 ug
EUR 327
Description: Rabbit Polyclonal NEIL3 antibody

NEIL3 Antibody
ABD4042 100 ug
EUR 438

NEIL3 antibody
10R-1522 100 ug
EUR 512
Description: Mouse monoclonal NEIL3 antibody

NEIL3 antibody
70R-18837 50 ul
EUR 435
Description: Rabbit polyclonal NEIL3 antibody

NEIL3 Antibody
DF4042 200ul
EUR 304
Description: NEIL3 Antibody detects endogenous levels of total NEIL3.

NEIL3 Antibody
1-CSB-PA003396
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000

NEIL3 Antibody
CSB-PA065468-
EUR 335
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
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Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

NEIL3 Antibody
CSB-PA065468-100ul 100ul
EUR 316
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
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Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

NEIL3 Antibody
1-CSB-PA015695GA01HU
  • EUR 597.00
  • EUR 333.00
  • 150ul
  • 50ul
  • Form: Liquid
  • Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles. Antigen Affinity Purified
Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
DLR-NEIL3-Mu-48T 48T
EUR 566
  • Should the Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
DLR-NEIL3-Mu-96T 96T
EUR 741
  • Should the Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
RD-NEIL3-Mu-48Tests 48 Tests
EUR 577

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
RD-NEIL3-Mu-96Tests 96 Tests
EUR 802

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
RDR-NEIL3-Mu-48Tests 48 Tests
EUR 603

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
RDR-NEIL3-Mu-96Tests 96 Tests
EUR 840

NEIL3 Polyclonal Antibody
ES2917-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against NEIL3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

NEIL3 Polyclonal Antibody
ES2917-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against NEIL3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

anti- NEIL3 antibody
FNab05649 100µg
EUR 585
  • Immunogen: nei endonuclease VIII-like 3(E. coli)
  • Uniprot ID: Q8TAT5
  • Gene ID: 55247
  • Research Area: Metabolism
Description: Antibody raised against NEIL3

NEIL3 Polyclonal Antibody
ABP51918-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540
  • Applications tips:
Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540

NEIL3 Polyclonal Antibody
ABP51918-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540
  • Applications tips:
Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540

NEIL3 Polyclonal Antibody
ABP51918-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540
  • Applications tips:
Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540

NEIL3 Polyclonal Antibody
41212-100ul 100ul
EUR 252

NEIL3 Polyclonal Antibody
41212-50ul 50ul
EUR 187

Anti-NEIL3 antibody
PAab05649 100 ug
EUR 412

Anti-NEIL3 antibody
STJ94396 200 µl
EUR 197
Description: Rabbit polyclonal to NEIL3.

NEIL3 siRNA
20-abx925706
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

NEIL3 siRNA
20-abx925707
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

NEIL3 Polyclonal Conjugated Antibody
C41212 100ul
EUR 397

Anti-NEIL3/Nei3 Antibody
A05497-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for NEIL3 Antibody (NEIL3) detection.tested for WB in Human, Mouse.

NEIL3 ELISA KIT|Human
EF005329 96 Tests
EUR 689

Human NEIL3 shRNA Plasmid
20-abx960591
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg
  • Shipped within 15-20 working days.

NEIL3 Recombinant Protein (Human)
RP078087 100 ug Ask for price

NEIL3 Blocking Peptide
20-abx063899
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
  • Shipped within 5-10 working days.

NEIL3 Blocking Peptide
DF4042-BP 1mg
EUR 195

NEIL3 ORF Vector (Human) (pORF)
ORF026030 1.0 ug DNA
EUR 405

NEIL3 ELISA Kit (Human) (OKEH05107)
OKEH05107 96 Wells
EUR 727
Description: Description of target: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.417 ng/mL

Mouse NEIL3 shRNA Plasmid
20-abx982114
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg
  • Shipped within 15-20 working days.

NEIL3 Recombinant Protein (Rat)
RP213656 100 ug Ask for price

NEIL3 Recombinant Protein (Mouse)
RP153635 100 ug Ask for price

NEIL3 sgRNA CRISPR Lentivector set (Human)
K1416101 3 x 1.0 ug
EUR 339

Neil3 ORF Vector (Rat) (pORF)
ORF071220 1.0 ug DNA
EUR 506

Neil3 ORF Vector (Mouse) (pORF)
ORF051213 1.0 ug DNA
EUR 506

NEIL3 ELISA Kit (Mouse) (OKCD09389)
OKCD09389 96 Wells
EUR 936
Description: Description of target: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.6 Publications;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.061ng/mL

NEIL3 ELISA Kit (Mouse) (OKEH03545)
OKEH03545 96 Wells
EUR 727
Description: Description of target: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.6 Publications;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.418 ng/mL

NEIL3 sgRNA CRISPR Lentivector (Human) (Target 1)
K1416102 1.0 ug DNA
EUR 154

NEIL3 sgRNA CRISPR Lentivector (Human) (Target 2)
K1416103 1.0 ug DNA
EUR 154

NEIL3 sgRNA CRISPR Lentivector (Human) (Target 3)
K1416104 1.0 ug DNA
EUR 154

NEIL3 Protein Vector (Human) (pPB-C-His)
PV104118 500 ng
EUR 552

NEIL3 Protein Vector (Human) (pPB-N-His)
PV104119 500 ng
EUR 552

NEIL3 Protein Vector (Human) (pPM-C-HA)
PV104120 500 ng
EUR 552

NEIL3 Protein Vector (Human) (pPM-C-His)
PV104121 500 ng
EUR 552

Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody
20-abx129922
  • EUR 467.00
  • EUR 133.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody
20-abx177722
  • EUR 1344.00
  • EUR 634.00
  • 1 mg
  • 200 ug
  • Please enquire.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody
20-abx325929
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody
abx331074-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Human NEIL3/ Endonuclease 8-like 3 ELISA Kit
E1730Hu 1 Kit
EUR 605

Human Endonuclease 8- like 3, NEIL3 ELISA KIT
ELI-45663h 96 Tests
EUR 824

Neil3 sgRNA CRISPR Lentivector set (Mouse)
K4227101 3 x 1.0 ug
EUR 339

Neil3 sgRNA CRISPR Lentivector set (Rat)
K6401001 3 x 1.0 ug
EUR 339

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody
20-abx008114
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody
abx030990-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody
abx030990-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody
20-abx014459
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody
abx235649-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Neil3 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K4227102 1.0 ug DNA
EUR 154

Neil3 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K4227103 1.0 ug DNA
EUR 154

Neil3 sgRNA CRISPR Lentivector (Mouse) (Target 3)
K4227104 1.0 ug DNA
EUR 154

Neil3 sgRNA CRISPR Lentivector (Rat) (Target 1)
K6401002 1.0 ug DNA
EUR 154

Neil3 sgRNA CRISPR Lentivector (Rat) (Target 2)
K6401003 1.0 ug DNA
EUR 154

Neil3 sgRNA CRISPR Lentivector (Rat) (Target 3)
K6401004 1.0 ug DNA
EUR 154

NEIL3 Protein Vector (Rat) (pPB-C-His)
PV284878 500 ng
EUR 603

NEIL3 Protein Vector (Rat) (pPB-N-His)
PV284879 500 ng
EUR 603

NEIL3 Protein Vector (Rat) (pPM-C-HA)
PV284880 500 ng
EUR 603

NEIL3 Protein Vector (Rat) (pPM-C-His)
PV284881 500 ng
EUR 603

NEIL3 Protein Vector (Mouse) (pPB-C-His)
PV204850 500 ng
EUR 603

NEIL3 Protein Vector (Mouse) (pPB-N-His)
PV204851 500 ng
EUR 603

NEIL3 Protein Vector (Mouse) (pPM-C-HA)
PV204852 500 ng
EUR 603

NEIL3 Protein Vector (Mouse) (pPM-C-His)
PV204853 500 ng
EUR 603

Neil3 3'UTR GFP Stable Cell Line
TU163982 1.0 ml Ask for price

Neil3 3'UTR Luciferase Stable Cell Line
TU213880 1.0 ml Ask for price

NEIL3 3'UTR Luciferase Stable Cell Line
TU015564 1.0 ml
EUR 1394

Neil3 3'UTR Luciferase Stable Cell Line
TU113982 1.0 ml Ask for price

NEIL3 3'UTR GFP Stable Cell Line
TU065564 1.0 ml
EUR 1394

Neil3 3'UTR GFP Stable Cell Line
TU263880 1.0 ml Ask for price

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse)
4-PAN291Mu01
  • EUR 266.00
  • EUR 2813.00
  • EUR 694.00
  • EUR 337.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: NEIL3 (Val2~Val187)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3)

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
K1416105 3 x 1.0 ug
EUR 376

Mouse Neil3/ Endonuclease 8-like 3 ELISA Kit
E1017Mo 1 Kit
EUR 632

Bovine Endonuclease 8- like 3, NEIL3 ELISA KIT
ELI-23242b 96 Tests
EUR 928

Mouse Endonuclease 8- like 3, Neil3 ELISA KIT
ELI-45664m 96 Tests
EUR 865

Mouse Neil3(Endonuclease 8-like 3) ELISA Kit
EM0777 96T
EUR 524.1
  • Detection range: 0.78-50 ng/ml
  • Uniprot ID: Q8K203
  • Alias: Neil3/Endonuclease 8-like 3/Nei-like protein 3/Endonuclease VIII-like 3/DNA glycosylase FPG2/DNA glycosylase/AP lyase Neil3
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.469 ng/ml

Recombinant Nei Endonuclease VIII Like Protein 3 (NEIL3)
4-RPN291Mu01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q8K203
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 23.9kDa
  • Isoelectric Point: Inquire
Description: Recombinant Mouse Nei Endonuclease VIII Like Protein 3 expressed in: E.coli

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), APC
4-PAN291Mu01-APC
  • EUR 374.00
  • EUR 3689.00
  • EUR 1016.00
  • EUR 481.00
  • EUR 232.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: NEIL3 (Val2~Val187)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with APC.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), Biotinylated
4-PAN291Mu01-Biotin
  • EUR 332.00
  • EUR 2763.00
  • EUR 803.00
  • EUR 411.00
  • EUR 228.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: NEIL3 (Val2~Val187)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with Biotin.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), Cy3
4-PAN291Mu01-Cy3
  • EUR 457.00
  • EUR 4877.00
  • EUR 1313.00
  • EUR 600.00
  • EUR 267.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: NEIL3 (Val2~Val187)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with Cy3.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), FITC
4-PAN291Mu01-FITC
  • EUR 319.00
  • EUR 2971.00
  • EUR 832.00
  • EUR 405.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: NEIL3 (Val2~Val187)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with FITC.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), HRP
4-PAN291Mu01-HRP
  • EUR 341.00
  • EUR 3213.00
  • EUR 897.00
  • EUR 433.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: NEIL3 (Val2~Val187)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with HRP.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), PE
4-PAN291Mu01-PE
  • EUR 319.00
  • EUR 2971.00
  • EUR 832.00
  • EUR 405.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: NEIL3 (Val2~Val187)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with PE.

Human Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) ELISA Kit
abx520380-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K1416106 1.0 ug DNA
EUR 167

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
K1416107 1.0 ug DNA
EUR 167

NEIL3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
K1416108 1.0 ug DNA
EUR 167

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) Protein
20-abx167933
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Nei Endonuclease VIII Like Protein 3 (NEIL3) Polyclonal Antibody (Mouse), APC-Cy7
4-PAN291Mu01-APC-Cy7
  • EUR 628.00
  • EUR 7258.00
  • EUR 1912.00
  • EUR 842.00
  • EUR 344.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: NEIL3 (Val2~Val187)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3). This antibody is labeled with APC-Cy7.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) CLIA Kit
20-abx496093
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

NEIL3 ELISA Kit| Bovine Endonuclease 8-like 3 ELISA Kit
EF011650 96 Tests
EUR 689

Neil3 ELISA Kit| Mouse Endonuclease 8-like 3 ELISA Kit
EF013387 96 Tests
EUR 689

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
20-abx154440
  • EUR 7504.00
  • EUR 3996.00
  • EUR 926.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
K4227105 3 x 1.0 ug
EUR 376

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
K6401005 3 x 1.0 ug
EUR 376

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
SEN291Mu-10x96wellstestplate 10x96-wells test plate
EUR 5333.64
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inte
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
SEN291Mu-1x48wellstestplate 1x48-wells test plate
EUR 526.89
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inte
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
SEN291Mu-1x96wellstestplate 1x96-wells test plate
EUR 709.84
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inte
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
SEN291Mu-5x96wellstestplate 5x96-wells test plate
EUR 2894.28
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inte
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) ELISA Kit
4-SEN291Mu
  • EUR 5384.00
  • EUR 2845.00
  • EUR 710.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Nei Endonuclease VIII Like Protein 3 elisa. Alternative names of the recognized antigen: FPG2
  • hFPG2
  • hNEI3
  • Endonuclease 8-like 3
  • DNA glycosylase FPG2
  • DNA glycosylase/AP lyase Neil3
  • Nei-like protein 3
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Nei Endonuclease VIII Like Protein 3 (NEIL3) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Cow Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) ELISA Kit
abx520379-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

ELISA kit for Mouse NEIL3 (Nei Endonuclease VIII Like Protein 3)
ELK8051 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Nei Endonuclease VIII Like Protein 3 (NEIL3). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody s
  • Show more
Description: A sandwich ELISA kit for detection of Nei Endonuclease VIII Like Protein 3 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Mouse Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) ELISA Kit
abx255125-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K4227106 1.0 ug DNA
EUR 167

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K4227107 1.0 ug DNA
EUR 167

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
K4227108 1.0 ug DNA
EUR 167

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
K6401006 1.0 ug DNA
EUR 167

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
K6401007 1.0 ug DNA
EUR 167

Neil3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
K6401008 1.0 ug DNA
EUR 167

human Albumin Antibody
BF0544 200ul
EUR 376
Description: human Albumin antibody detects endogenous levels of total human Albumin.

Human P16 Antibody
BF0580 200ul
EUR 376
Description: Human P16 antibody detects endogenous levels of total Human P16.

human Splunc2 Antibody
BF0019 200ul
EUR 376
Description: human Splunc2 antibody detects endogenous levels of total human Splunc2.

human VEGF Antibody
E13-a001 100μg
EUR 382

Human IgE antibody
E22NH04-1 100ug
EUR 343

Human P16 Antibody
abx011302-100ul 100 ul
EUR 411
  • Shipped within 5-10 working days.

Human HER2 Antibody
abx023907-100ug 100 ug
EUR 453
  • Shipped within 5-10 working days.

Human Merlin Antibody
abx023908-100ug 100 ug
EUR 453
  • Shipped within 5-10 working days.

Human CRP Antibody
abx023919-10ml 10 ml
EUR 356
  • Shipped within 5-10 working days.

Human IgM Antibody
abx015702-100ul 100 ul
EUR 411
  • Shipped within 5-10 working days.

human Splunc2 Antibody
abx015999-100ug 100 ug
EUR 411
  • Shipped within 5-10 working days.

Human IgA Antibody
abx019197-1mg 1 mg
EUR 565
  • Shipped within 5-10 working days.

Human IgG Antibody
abx019200-5mg 5 mg
EUR 230
  • Shipped within 5-10 working days.

Human IgA Antibody
abx234075-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Human IgA Antibody
abx234076-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Human IgG Antibody
abx234077-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Human Albumin antibody
70R-7567 1 mg
EUR 140
Description: Affinity purified Goat polyclonal Human Albumin antibody

Human PPP2R1A Antibody
35179-05111 150 ug
EUR 261

Human Cystathionase Antibody
35613-05111 150 ug
EUR 261

Human Amisyn Antibody
35627-05111 150 ug
EUR 261

Human PDCL3 Antibody
35628-05111 150 ug
EUR 261

Human LRP2BP Antibody
35629-05111 150 ug
EUR 261

Human Enterokinase Antibody
35631-05111 150 ug
EUR 261

Human GAD67 Antibody
35633-05111 150 ug
EUR 261

Human CYB5R3 Antibody
35634-05111 150 ug
EUR 261

Human CD37 Antibody
35636-05111 150 ug
EUR 261

Human SH3GL3 Antibody
35637-05111 150 ug
EUR 261

Human XRCC2 Antibody
35678-05111 150 ug
EUR 261

Human EEF1A1 Antibody
35679-05111 150 ug
EUR 261

Human GFPT1 Antibody
35680-05111 150 ug
EUR 261

Human SDF2 Antibody
35683-05111 150 ug
EUR 261

Human LCMT1 Antibody
35684-05111 150 ug
EUR 261

Human HMBS Antibody
35685-05111 150 ug
EUR 261

Human CD1E Antibody
35696-05111 150 ug
EUR 261

Human CD3G Antibody
35697-05111 150 ug
EUR 261

Human CD9 Antibody
35698-05111 150 ug
EUR 261

Human UBE2L3 Antibody
35778-05111 150 ug
EUR 261

Human PITPN Antibody
34035-05111 150 ug
EUR 261

Human GTSF1 Antibody
35138-05111 150 ug
EUR 261

Human Hemopexin Antibody
35139-05111 150 ug
EUR 261

Human LOX Antibody
35140-05111 150 ug
EUR 261

Human Thrombin Antibody
35147-05111 150 ug
EUR 261

Human UBTD2 Antibody
33376-05111 150 ug
EUR 261

Human LOC51255 Antibody
33377-05111 150 ug
EUR 261

Human IFT20 Antibody
33379-05111 150 ug
EUR 261

Human COMMD9 Antibody
33380-05111 150 ug
EUR 261

Human UBE2M Antibody
33381-05111 150 ug
EUR 261

Human CIAO1 Antibody
33382-05111 150 ug
EUR 261

Human SMUG1 Antibody
33383-05111 150 ug
EUR 261

Human NMRAL1 Antibody
33384-05111 150 ug
EUR 261

Human SSR4 Antibody
33385-05111 150 ug
EUR 261
Our work deciphers repeat-variable diresidues for 5-methylcytosine and 5-hydroxymethylcytosine, and offers instruments for TALE-dependent epigenome recognition.Transcription activator-like effector proteins recognise particular DNA sequences by way of tandem repeats. Here the authors show TALEs can recognise the methylated bases 5mC and 5hmC, enabling them to detect epigenetic modifications.

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