Transcription activator-like effectors (TALEs) are proteins discovered within the genus Xanthomonas of phytopathogenic micro organism. These proteins enter the nucleus of cells within the host plant and can induce the expression of susceptibility genes (S genes), triggering illness. TALEs bind the promoter area of S genes following a particular code, which permits the prediction of binding websites based mostly on TALEs amino acid sequences.
New candidate S genes can then be found by discovering the intersection between genes induced within the presence of TALEs and genes containing predicted effector binding components. By contrasting differential expression data and binding website predictions throughout totally different datasets, patterns of TALE diversification or convergence could also be unveiled, however this requires the seamless integration of various genomic and transcriptomic data.
With this in thoughts, we current daTALbase, a curated relational database that integrates TALE-related data together with bacterial TALE sequences, plant promoter sequences, predicted TALE binding websites, transcriptomic data of host crops in response to TALE-harboring micro organism, and different related data. The database might be explored to uncover new candidate S genes in addition to to research variation in TALE repertories and their corresponding targets. The first model of the database right here offered consists of data for Oryza sp.-Xanthomonas pv. oryzae interactions. Future variations of the database will incorporate info for different pathosystems involving TALEs.
The impact of accelerating numbers of repeats on TAL effector DNA binding specificity.
Transcription activator-like effectors (TALEs) acknowledge their DNA targets by way of tandem repeats, every specifying a single nucleotide base in a one-to-one sequential association. Due to this modularity and their capacity to bind lengthy DNA sequences with excessive specificity, TALEs have been utilized in many functions. Contributions of particular person repeat-nucleotide associations to affinity and specificity have been characterised.
Here, utilizing in vitro binding assays, we examined the connection between the variety of repeats in a TALE and its affinity, for each goal and non-target DNA. Each extra repeat offers additional binding power for the goal DNA, with the acquire decaying exponentially such that binding power saturates. Affinity for non-target DNA additionally will increase non-linearly with the variety of repeats, however with a slower decay of acquire.
The distinction between the impact of size on affinity for goal versus non-target DNA manifests in specificity growing then diminishing with growing TALE size, peaking between 15 and 19 repeats. Modeling throughout totally different hypothetical saturation ranges and charges of acquire decay, reflecting totally different repeat compositions, yielded a comparable vary of specificity optima. This vary encompasses the imply and median size of native TALEs, suggesting that these proteins as a group have developed for most specificity.
Targeted promoter enhancing for rice resistance to Xanthomonas oryzae pv. oryzae reveals differential actions for SWEET14-inducing TAL effectors.
As a key virulence technique to trigger bacterial leaf blight, Xanthomonas oryzae pv. oryzae (Xoo) injects into the plant cell DNA-binding proteins referred to as transcription activator-like effectors (TALEs) that bind to effector-binding components (EBEs) in a sequence-specific method, leading to host gene induction. TALEs AvrXa7, PthXo3, TalC and Tal5, present in geographically distant Xoo strains, all goal OsSWEET14, thus thought of as a pivotal TALE goal performing as main susceptibility issue throughout rice-Xoo interactions.
Here, we report the technology of an allele library of the OsSWEET14 promoter via steady expression of TALE-nuclease (TALEN) constructs in rice. The susceptibility stage of traces carrying mutations in AvrXa7, Tal5 or TalC EBEs was assessed. Plants edited in AvrXa7 or Tal5 EBEs have been resistant to bacterial strains counting on the corresponding TALE. Surprisingly, though indels inside TalC EBE prevented OsSWEET14 induction in response to BAI3 wild-type micro organism counting on TalC, lack of TalC responsiveness failed to confer resistance to this pressure.
The TalC EBE mutant line was, nevertheless, resistant to a pressure expressing a synthetic SWEET14-inducing TALE whose EBE was additionally edited on this line. This work gives the primary set of alleles edited in TalC EBE and uncovers a distinct, broader vary of actions for TalC in contrast to AvrXa7 or Tal5. We suggest the existence of extra targets for TalC past SWEET14, suggesting that TALE-mediated plant susceptibility might consequence from induction of a number of, genetically redundant, host susceptibility genes by a single effector.
Deciphering TAL effectors for 5-methylcytosine and 5-hydroxymethylcytosine recognition.
DNA recognition by transcription activator-like effector (TALE) proteins is mediated by tandem repeats that specify nucleotides via repeat-variable diresidues. These repeat-variable diresidues type direct and sequence-specific contacts to DNA bases; therefore, TALE-DNA interplay is delicate to DNA chemical modifications. Here we conduct a thorough investigation, overlaying all theoretical repeat-variable diresidue combos, for their recognition capabilities for 5-methylcytosine and 5-hydroxymethylcytosine, two vital epigenetic markers in greater eukaryotes.
We determine each particular and degenerate repeat-variable diresidues for 5-methylcytosine and 5-hydroxymethylcytosine. Utilizing these novel repeat-variable diresidues, we obtain methylation-dependent gene activation and genome enhancing in vivo; we additionally report base-resolution detection of 5hmC in an in vitro assay.
NEIL3 Antibody |
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| CSB-PA855036XA01HU-10mg | Cusabio | 10mg | Ask for price |
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Description: Recombinant Homo sapiens (Human) NEIL3 protein |
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NEIL3 Antibody |
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| 1-CSB-PA015695GA01HU | Cusabio |
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Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
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NEIL3 Antibody |
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| DF4042 | Affbiotech | 200ul | 420 EUR |
NEIL3 Antibody |
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| DF4042-100ul | Affinity Biosciences | 100ul | 168 EUR |
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Description: WB,IF/ICC,ELISA(peptide) |
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NEIL3 Antibody |
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| DF4042-200ul | Affinity Biosciences | 200ul | 210 EUR |
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Description: WB,IF/ICC,ELISA(peptide) |
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Neil3 Antibody |
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| CSB-PA809085XA01MO-02mg | Cusabio | 0.2mg | Ask for price |
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Description: Recombinant Mus musculus (Mouse) Neil3 protein |
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Neil3 Antibody |
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| CSB-PA809085XA01MO-10mg | Cusabio | 10mg | Ask for price |
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Description: Recombinant Mus musculus (Mouse) Neil3 protein |
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NEIL3 Antibody |
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| C15635-100ul | Assay Biotech | 100μl | 217 EUR |
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Description: NEIL3 Rabbit Polyclonal Antibody |
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NEIL3 Antibody |
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| C15635-50ul | Assay Biotech | 50μl | 143.5 EUR |
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Description: NEIL3 Rabbit Polyclonal Antibody |
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NEIL3 Antibody |
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| CSB-PA065468- | Cusabio | each | 402 EUR |
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Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
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NEIL3 Antibody |
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| CSB-PA065468-100ul | Cusabio | 100ul | 379.2 EUR |
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Description: A polyclonal antibody against NEIL3. Recognizes NEIL3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
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NEIL3 Antibody |
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| E11-15635C | EnoGene | 100μg | 225 EUR |
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Description: Available in various conjugation types. |
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NEIL3 Antibody |
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| E19-4042 | EnoGene | 100μg/100μl | 225 EUR |
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Description: Available in various conjugation types. |
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NEIL3 Antibody |
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| E38PA2705 | EnoGene | 100ul | 225 EUR |
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Description: Available in various conjugation types. |
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NEIL3 Antibody |
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| MBS5315642-01mL | MyBiosource | 0.1mL | 470 EUR |
NEIL3 Antibody |
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| MBS5315642-5x01mL | MyBiosource | 5x0.1mL | 1955 EUR |
NEIL3 Antibody |
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| MBS7131342-01mL | MyBiosource | 0.1mL | 270 EUR |
NEIL3 Antibody |
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| MBS7131342-5x01mL | MyBiosource | 5x0.1mL | 1200 EUR |
NEIL3 Antibody |
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| MBS7116686-005mg | MyBiosource | 0.05mg | 150 EUR |
NEIL3 Antibody |
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| MBS7116686-01mg | MyBiosource | 0.1mg | 190 EUR |
NEIL3 Antibody |
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| MBS7116686-5x01mg | MyBiosource | 5x0.1mg | 845 EUR |
NEIL3 Antibody |
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| MBS9605498-01mL | MyBiosource | 0.1mL | 260 EUR |
NEIL3 Antibody |
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| MBS9605498-02mL | MyBiosource | 0.2mL | 305 EUR |
NEIL3 Antibody |
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| MBS9605498-5x02mL | MyBiosource | 5x0.2mL | 1220 EUR |
NEIL3 Antibody |
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| MBS8581502-01mL | MyBiosource | 0.1mL | 305 EUR |
NEIL3 Antibody |
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| MBS8581502-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 465 EUR |
NEIL3 Antibody |
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| MBS8581502-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 465 EUR |
NEIL3 Antibody |
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| MBS8581502-01mLAF610 | MyBiosource | 0.1mL(AF610) | 465 EUR |
NEIL3 Antibody |
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| MBS8581502-01mLAF635 | MyBiosource | 0.1mL(AF635) | 465 EUR |
NEIL3 Antibody |
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| MBS9201583-01mL | MyBiosource | 0.1mL | 415 EUR |
NEIL3 Antibody |
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| MBS9201583-5x01mL | MyBiosource | 5x0.1mL | 1841 EUR |
NEIL3 Antibody |
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| MBS8514749-01mg | MyBiosource | 0.1mg | 305 EUR |
NEIL3 Antibody |
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| MBS8514749-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 465 EUR |
NEIL3 Antibody |
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| MBS8514749-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 465 EUR |
NEIL3 Antibody |
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| MBS8514749-01mLAF610 | MyBiosource | 0.1mL(AF610) | 465 EUR |
NEIL3 Antibody |
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| MBS8514749-01mLAF635 | MyBiosource | 0.1mL(AF635) | 465 EUR |
NEIL3 Antibody |
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| MBS851221-01mg | MyBiosource | 0.1mg | 305 EUR |
NEIL3 Antibody |
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| MBS851221-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 465 EUR |
NEIL3 Antibody |
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| MBS851221-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 465 EUR |
NEIL3 Antibody |
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| MBS851221-01mLAF610 | MyBiosource | 0.1mL(AF610) | 465 EUR |
NEIL3 Antibody |
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| MBS851221-01mLAF635 | MyBiosource | 0.1mL(AF635) | 465 EUR |
NEIL3 Antibody |
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| MBS9506350-005mL | MyBiosource | 0.05mL | 285 EUR |
NEIL3 Antibody |
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| MBS9506350-01mL | MyBiosource | 0.1mL | 385 EUR |
NEIL3 Antibody |
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| MBS9506350-5x01mL | MyBiosource | 5x0.1mL | 1590 EUR |
anti- NEIL3 antibody |
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| FNab05649 | FN Test | 100µg | 702 EUR |
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Description: Antibody raised against NEIL3 |
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NEIL3 Antibody (Center) |
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| E45R31826G-1 | EnoGene | 100 ul | 395 EUR |
NEIL3 Antibody (Center) |
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| E45R31826G-4 | EnoGene | 50 ul | 295 EUR |
NEIL3 Antibody (Center) |
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| MBS9215199-008mL | MyBiosource | 0.08mL | 210 EUR |
NEIL3 Antibody (Center) |
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| MBS9215199-04mL | MyBiosource | 0.4mL | 430 EUR |
NEIL3 Antibody (Center) |
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| MBS9215199-5x04mL | MyBiosource | 5x0.4mL | 1910 EUR |
NEIL3 Polyclonal Antibody |
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| 41212-100ul | SAB | 100ul | 302.4 EUR |
NEIL3 Polyclonal Antibody |
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| 41212-50ul | SAB | 50ul | 224.4 EUR |
NEIL3 Polyclonal Antibody |
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| ABP51918-003ml | Abbkine | 0.03ml | 189.6 EUR |
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Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540 |
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NEIL3 Polyclonal Antibody |
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| ABP51918-01ml | Abbkine | 0.1ml | 346.8 EUR |
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Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540 |
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NEIL3 Polyclonal Antibody |
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| ABP51918-02ml | Abbkine | 0.2ml | 496.8 EUR |
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Description: A polyclonal antibody for detection of NEIL3 from Human, Mouse. This NEIL3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540 |
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NEIL3 polyclonal antibody |
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| BS61905 | Bioworld Biotech | 50ul | 275 EUR |
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Description: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
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NEIL3 Polyclonal Antibody |
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| BT-AP05878-100ul | Jiaxing Korain Biotech Ltd (BT Labs) | 100ul | Ask for price |
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Description: NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. |
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NEIL3 Polyclonal Antibody |
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| BT-AP05878-20ul | Jiaxing Korain Biotech Ltd (BT Labs) | 20ul | Ask for price |
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Description: NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. |
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NEIL3 Polyclonal Antibody |
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| BT-AP05878-50ul | Jiaxing Korain Biotech Ltd (BT Labs) | 50ul | Ask for price |
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Description: NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. |
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NEIL3 Polyclonal Antibody |
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| JOT-AP05878-100ul | Jotbody | 100ul | 220 EUR |
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Description: Human;Mouse |
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NEIL3 Polyclonal Antibody |
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| JOT-AP05878-50ul | Jotbody | 50ul | 144 EUR |
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Description: Human;Mouse |
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NEIL3 Polyclonal Antibody |
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| E041212 | EnoGene | 100μg/100μl | 255 EUR |
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Description: Available in various conjugation types. |
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NEIL3 Polyclonal Antibody |
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| E44H05440 | EnoGene | 100ul | 255 EUR |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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NEIL3 Polyclonal Antibody |
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| E20-73031 | EnoGene | 100ug | 225 EUR |
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Description: Available in various conjugation types. |
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NEIL3 Polyclonal Antibody |
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| E96819 | EnoGene | 100ul | 225 EUR |
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Description: Available in various conjugation types. |
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NEIL3 Polyclonal Antibody |
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| MBS2539246-002mL | MyBiosource | 0.02mL | 140 EUR |
NEIL3 Polyclonal Antibody |
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| MBS2539246-006mL | MyBiosource | 0.06mL | 180 EUR |
NEIL3 Polyclonal Antibody |
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| MBS2539246-012mL | MyBiosource | 0.12mL | 260 EUR |
NEIL3 Polyclonal Antibody |
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| MBS2539246-02mL | MyBiosource | 0.2mL | 405 EUR |
NEIL3 Polyclonal Antibody |
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| MBS8573105-01mL | MyBiosource | 0.1mL | 305 EUR |
NEIL3 Polyclonal Antibody |
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| MBS8573105-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 565 EUR |
NEIL3 Polyclonal Antibody |
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| MBS8573105-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 565 EUR |
NEIL3 Polyclonal Antibody |
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| MBS8573105-01mLAF610 | MyBiosource | 0.1mL(AF610) | 565 EUR |
NEIL3 Polyclonal Antibody |
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| MBS8573105-01mLAF635 | MyBiosource | 0.1mL(AF635) | 565 EUR |
NEIL3 Polyclonal Antibody |
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| MBS9244457-01mL | MyBiosource | 0.1mL | 415 EUR |
NEIL3 Polyclonal Antibody |
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| MBS9244457-5x01mL | MyBiosource | 5x0.1mL | 1841 EUR |
NEIL3 Polyclonal Antibody |
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| MBS8524012-01mg | MyBiosource | 0.1mg | 305 EUR |
NEIL3 Polyclonal Antibody |
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| MBS8524012-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 465 EUR |
NEIL3 Polyclonal Antibody |
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| MBS8524012-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 465 EUR |
NEIL3 Polyclonal Antibody |
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| MBS8524012-01mLAF610 | MyBiosource | 0.1mL(AF610) | 465 EUR |
NEIL3 Polyclonal Antibody |
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| MBS8524012-01mLAF635 | MyBiosource | 0.1mL(AF635) | 465 EUR |
NEIL3 Polyclonal Antibody |
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| MBS9412161-005mL | MyBiosource | 0.05mL | 245 EUR |
NEIL3 Polyclonal Antibody |
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| MBS9412161-01mL | MyBiosource | 0.1mL | 305 EUR |
NEIL3 Polyclonal Antibody |
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| MBS9412161-5x01mL | MyBiosource | 5x0.1mL | 1230 EUR |
NEIL3 Polyclonal Antibody |
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| UB-GEN-1852 | UpingBio | 100 ul | 200 EUR |
Rabbit anti-Homo sapiens (Human) NEIL3 Polyclonal Antibody |
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| MBS9006219-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Anti-EPHA10 NEIL3 Antibody |
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| A05497 | BosterBio | 100ul | 360 EUR |
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Description: Boster Bio Anti-EPHA10 NEIL3 Antibody (Catalog # A05497). Tested in WB applications. This antibody reacts with Human. |
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Human NEIL3 siRNA |
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| 20-abx925707 | Abbexa |
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NEIL3 Antibody - middle region |
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| MBS3220075-01mL | MyBiosource | 0.1mL | 455 EUR |
NEIL3 Antibody - middle region |
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| MBS3220075-5x01mL | MyBiosource | 5x0.1mL | 1995 EUR |
OACD05928-1ML - NEIL3 Antibody |
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| OACD05928-1ML | Aviva Systems Biology | 1ml | 759 EUR |
OAAJ04914-100UL - NEIL3 Antibody |
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| OAAJ04914-100UL | Aviva Systems Biology | 100uL | 319 EUR |
OACD05928-100UL - NEIL3 Antibody |
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| OACD05928-100UL | Aviva Systems Biology | 100ul | 219 EUR |
NEIL3 siRNA (Human) |
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| MBS8218100-15nmol | MyBiosource | 15nmol | 405 EUR |
NEIL3 siRNA (Human) |
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| MBS8218100-30nmol | MyBiosource | 30nmol | 565 EUR |
NEIL3 siRNA (Human) |
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| MBS8218100-5x30nmol | MyBiosource | 5x30nmol | 2450 EUR |
Recombinant Human NEIL3 |
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| MBS7613431-005mg | MyBiosource | 0.05mg | 405 EUR |
Recombinant Human NEIL3 |
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| MBS7613431-02mg | MyBiosource | 0.2mg | 760 EUR |
Recombinant Human NEIL3 |
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| MBS7613431-1mg | MyBiosource | 1mg | 2175 EUR |
Recombinant Human NEIL3 |
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| MBS7613431-5x1mg | MyBiosource | 5x1mg | 8410 EUR |
NEIL3 Rabbit Polyclonal Antibody |
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| ES2917-100ul | ELK Biotech | 100ul | 124 EUR |
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Description: WB, IHC, ELISA |
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NEIL3 Rabbit Polyclonal Antibody |
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| ES2917-50ul | ELK Biotech | 50ul | 74 EUR |
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Description: WB, IHC, ELISA |
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Mouse monoclonal antibody Anti-Human NEIL3 |
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| MBS120331-01mg | MyBiosource | 0.1mg | 470 EUR |
Mouse monoclonal antibody Anti-Human NEIL3 |
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| MBS120331-5x01mg | MyBiosource | 5x0.1mg | 2080 EUR |
NEIL3 Antibody(Center) Blocking peptide |
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| MBS9224277-INQUIRE | MyBiosource | INQUIRE | Ask for price |
NEIL3 Polyclonal Conjugated Antibody |
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| C41212 | SAB | 100ul | 476.4 EUR |
NEIL3 Polyclonal Conjugated Antibody |
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| MBS9449961-01mLAF350 | MyBiosource | 0.1mL(AF350) | 480 EUR |
NEIL3 Polyclonal Conjugated Antibody |
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| MBS9449961-01mLAF405 | MyBiosource | 0.1mL(AF405) | 480 EUR |
NEIL3 Polyclonal Conjugated Antibody |
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| MBS9449961-01mLAF488 | MyBiosource | 0.1mL(AF488) | 480 EUR |
NEIL3 Polyclonal Conjugated Antibody |
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| MBS9449961-01mLAF555 | MyBiosource | 0.1mL(AF555) | 480 EUR |
NEIL3 Polyclonal Conjugated Antibody |
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| MBS9449961-01mLBiotin | MyBiosource | 0.1mL(Biotin) | 480 EUR |
Human NEIL3 shRNA Plasmid |
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| 20-abx960591 | Abbexa |
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NEIL3 ELISA KIT|Human |
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| EF005329 | Lifescience Market | 96 Tests | 826.8 EUR |
Human NEIL3 Protein Lysate |
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| MBS8415935-002mg | MyBiosource | 0.02mg | 365 EUR |
Human NEIL3 Protein Lysate |
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| MBS8415935-5x002mg | MyBiosource | 5x0.02mg | 1410 EUR |
Anti-NEI3/NEIL3 Antibody (aa491-540) |
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| MBS2401556-005mL | MyBiosource | 0.05mL | 595 EUR |
Anti-NEI3/NEIL3 Antibody (aa491-540) |
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| MBS2401556-5x005mL | MyBiosource | 5x0.05mL | 2500 EUR |
NEIL3 (untagged)-Human nei endonuclease VIII-like 3 (E. coli) (NEIL3) |
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| SC319567 | Origene Technologies GmbH | 10 µg | Ask for price |
NEIL3 Recombinant Protein (Human) |
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| RP078087 | ABM | 100 ug | Ask for price |
NEIL3(Center) Rabbit Polyclonal Antibody |
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| E10G34728 | EnoGene | 100 μl | 275 EUR |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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ARP75647_P050-25UL - NEIL3 Antibody - middle region |
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| ARP75647_P050-25UL | Aviva Systems Biology | 25ul | 99 EUR |
NEIL3 (GFP-tagged) - Human nei endonuclease VIII-like 3 (E. coli) (NEIL3) |
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| RG206838 | Origene Technologies GmbH | 10 µg | Ask for price |
Human NEIL3 knockout cell line |
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| ABC-KH10006 | AcceGen | 1 vial | Ask for price |
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Description: Human NEIL3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human NEIL3 knockdown cell line |
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| ABC-KD10006 | AcceGen | 1 vial | Ask for price |
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Description: Human NEIL3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human NEIL3 Protein Lysate 20ug |
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| IHUNEIL3PLLY20UG | Innovative research | each | 213 EUR |
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Description: Human NEIL3 Protein Lysate 20ug |
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NEIL3 ORF Vector (Human) (pORF) |
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| ORF026030 | ABM | 1.0 ug DNA | 486 EUR |
ARP75647_P050 - NEIL3 Antibody - middle region (ARP75647_P050) |
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| ARP75647_P050 | Aviva Systems Biology | 100ul | 389 EUR |
NEIL3 ELISA Kit (Human) (OKEH05107) |
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| OKEH05107 | Aviva Systems Biology | 96 Wells | 872.4 EUR |
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Description: Description of target: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.417 ng/mL |
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Anti-Endonuclease 8-like 3 NEIL3 Antibody |
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| A05497-3 | BosterBio | 100ul | 380 EUR |
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Description: Boster Bio Anti-Endonuclease 8-like 3 NEIL3 Antibody catalog # A05497-3. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse. |
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NEIL3 (Myc-DDK-tagged)-Human nei endonuclease VIII-like 3 (E. coli) (NEIL3) |
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| RC206838 | Origene Technologies GmbH | 10 µg | Ask for price |
OASG04892-100UL - NEIL3 Antibody - C-terminal region |
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| OASG04892-100UL | Aviva Systems Biology | 100ul | 239 EUR |
NEI3 (NEIL3) (NM_018248) Human Over-expression Lysate |
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| E45H10655-2 | EnoGene | each | 395 EUR |
NEI3 (NEIL3) (NM_018248) Human Over-expression Lysate |
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| LS055247 | BosterBio | 100ug | 628 EUR |
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Description: Transient overexpression lysate of nei endonuclease VIII-like 3 (E. coli) (NEIL3) |
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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody |
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| abx114043-100l | Abbexa | 100 µl | 612.5 EUR |
Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody |
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| abx331074-100ul | Abbexa | 100 ul | 510 EUR |
Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody |
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| abx129922-100l | Abbexa | 100 µl | 287.5 EUR |
Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody |
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| 20-abx129922 | Abbexa |
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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody |
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| abx129922-1ml | Abbexa | 1 ml | 850 EUR |
Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody |
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| abx129922-200l | Abbexa | 200 µl | 375 EUR |
Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody |
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| 20-abx177722 | Abbexa |
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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody |
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| abx325929-100g | Abbexa | 100 µg | 250 EUR |
Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody |
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| 20-abx325929 | Abbexa |
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Nei Endonuclease VIII Like Protein 3 (NEIL3) Antibody |
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| abx325929-50g | Abbexa | 50 µg | 187.5 EUR |
NEI3 (NEIL3) (164-177) rabbit polyclonal antibody, Aff - Purified |
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| AP23595PU-N | Origene Technologies GmbH | 50 µg | Ask for price |
OKEH05107-96W - NEIL3 ELISA Kit (Human) |
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| OKEH05107-96W | Aviva Systems Biology | 96Wells | 600 EUR |
NEIL3 sgRNA CRISPR Lentivector set (Human) |
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| K1416101 | ABM | 3 x 1.0 ug | 406.8 EUR |
Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody |
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| abx030990-400l | Abbexa | 400 µl | 518.75 EUR |
Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody |
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| abx030990-400ul | Abbexa | 400 ul | 627.6 EUR |
Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody |
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| abx030990-80l | Abbexa | 80 µl | 281.25 EUR |
Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody |
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| abx014459-100g | Abbexa | 100 µg | 43.75 EUR |
Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody |
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| 20-abx014459 | Abbexa |
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Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody |
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| 20-abx008114 | Abbexa |
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Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody |
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| abx235649-100g | Abbexa | 100 µg | 350 EUR |
Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Antibody |
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| abx235649-100ug | Abbexa | 100 ug | 661.2 EUR |
NEIL3 Protein Vector (Human) (pPM-C-HA) |
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| PV104120 | ABM | 500 ng | 662.4 EUR |
NEIL3 Protein Vector (Human) (pPB-C-His) |
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| PV104118 | ABM | 500 ng | 662.4 EUR |
NEIL3 Protein Vector (Human) (pPB-N-His) |
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| PV104119 | ABM | 500 ng | 662.4 EUR |
NEIL3 Protein Vector (Human) (pPM-C-His) |
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| PV104121 | ABM | 500 ng | 662.4 EUR |
Human NEIL3 Over-expressing Stable Cell Line |
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| ABC-X2020 | AcceGen | 1 vial | Ask for price |
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Description: Gentaur can provide custom lentiviral constructs expressing any genes of interest as long as it is less than about 3 kb. Lentiviral technology enables us to efficiently generate stable expression lines which are then selected for moderate or high expressers, depending on the experimental requirements. If you are interested in specific lentiviral DNA constructs or have further questions, please contact us to discuss the details. NEIL3 nei endonuclease VIII-like 3 (E. coli) [ Homo sapiens ] http://www.ncbi.nlm.nih.gov/gene/55247 |
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Rabbit anti-Mus musculus (Mouse) NEIL3 Polyclonal Antibody |
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| MBS9001922-INQUIRE | MyBiosource | INQUIRE | Ask for price |
NEIL3 sgRNA CRISPR Lentivector (Human) (Target 1) |
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| K1416102 | ABM | 1.0 ug DNA | 184.8 EUR |
NEIL3 sgRNA CRISPR Lentivector (Human) (Target 2) |
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| K1416103 | ABM | 1.0 ug DNA | 184.8 EUR |
NEIL3 sgRNA CRISPR Lentivector (Human) (Target 3) |
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| K1416104 | ABM | 1.0 ug DNA | 184.8 EUR |
Human NEIL3/ Endonuclease 8-like 3 ELISA Kit |
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| E1730Hu | Sunlong | 1 Kit | 515 EUR |
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Description: DNA glycosylase FPG2,DNA glycosylase/AP lyase Neil3,Endonuclease VIII-like 3,Nei-like protein 3 |
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Recombinant Human Endonuclease 8-like 3 (NEIL3) |
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| MBS1313224-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | 1460 EUR |
Recombinant Human Endonuclease 8-like 3 (NEIL3) |
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| MBS1313224-002mgEColi | MyBiosource | 0.02mg(E-Coli) | 1160 EUR |
Recombinant Human Endonuclease 8-like 3 (NEIL3) |
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| MBS1313224-002mgYeast | MyBiosource | 0.02mg(Yeast) | 1220 EUR |
Recombinant Human Endonuclease 8-like 3 (NEIL3) |
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| MBS1313224-01mgEColi | MyBiosource | 0.1mg(E-Coli) | 1395 EUR |
Recombinant Human Endonuclease 8-like 3 (NEIL3) |
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| MBS1313224-01mgYeast | MyBiosource | 0.1mg(Yeast) | 1435 EUR |
Lenti ORF particles, NEIL3 (mGFP-tagged) - Human nei endonuclease VIII-like 3 (E. coli) (NEIL3), 200ul, >10^7 TU/mL |
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| RC206838L2V | Origene Technologies GmbH | 200 µl | Ask for price |
Lenti ORF particles, NEIL3 (mGFP-tagged) - Human nei endonuclease VIII-like 3 (E. coli) (NEIL3), 200ul, >10^7 TU/mL |
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| RC206838L4V | Origene Technologies GmbH | 200 µl | Ask for price |
Human Endonuclease 8- like 3, NEIL3 ELISA KIT |
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| ELI-45663h | Lifescience Market | 96 Tests | 988.8 EUR |
Recombinant Human NEIL3 Protein, His (Fc)-Avi-tagged |
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| NEIL3-3609H | Creative BioMart | 50ug | 2398.4 EUR |
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Description: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
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Human Endonuclease 8-like 3, NEIL3 ELISA Kit |
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| MBS9341634-10x96StripWells | MyBiosource | 10x96-Strip-Wells | 6725 EUR |
Human Endonuclease 8-like 3, NEIL3 ELISA Kit |
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| MBS9341634-48StripWells | MyBiosource | 48-Strip-Wells | 550 EUR |
Human Endonuclease 8-like 3, NEIL3 ELISA Kit |
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| MBS9341634-5x96StripWells | MyBiosource | 5x96-Strip-Wells | 3420 EUR |
Human Endonuclease 8-like 3, NEIL3 ELISA Kit |
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| MBS9341634-96StripWells | MyBiosource | 96-Strip-Wells | 765 EUR |
Our work deciphers repeat-variable diresidues for 5-methylcytosine and 5-hydroxymethylcytosine, and offers instruments for TALE-dependent epigenome recognition.Transcription activator-like effector proteins recognise particular DNA sequences by way of tandem repeats. Here the authors show TALEs can recognise the methylated bases 5mC and 5hmC, enabling them to detect epigenetic modifications.
