Inducible modulation is usually required for exact investigations and manipulations of dynamic organic processes. Transcription activator-like effectors (TALEs) present a robust device for focused gene modifying and transcriptional programming. We designed a sequence of chemical inducible methods by coupling TALEs with a mutated human estrogen receptor (ERT2), which renders them 4-hydroxyl-tamoxifen (4-OHT) inducible for entry of the genome.
Chemical inducible genome modifying was achieved by way of fusing two tandem ERT2 domains to personalised transcription activator-like effector nuclease (TALEN), which we termed “Hybrid Inducible Technology” (HIT-TALEN). Those for transcription activation had been vigorously optimized utilizing a number of assemble designs. Most environment friendly drug induction for endogenous gene activation was achieved with minimal background exercise utilizing an optimized inducible TALE based mostly SunTag system (HIT-TALE-SunTag).
The HIT-SunTag system is fast, tunable, selective to 4-OHT over an endogenous ligand, and reversible in drug induced transcriptional activation. Versatile methods developed on this research may be simply utilized for modifying and transcriptional programming of doubtless any genomic loci in a good and efficient chemical inducible trend.
Xanthomonas TAL effectors hijack host basal transcription issue IIA α and γ subunits for invasion.
The Xanthomonas genus consists of Gram-negative plant-pathogenic micro organism, which infect a broad vary of crops and wild plant species, trigger signs with leaf blights, streaks, spots, stripes, necrosis, wilt, cankers and gummosis on leaves, stems and fruits in all kinds of crops by way of injecting their effector proteins into the host cell throughout an infection. Among these virulent effectors, transcription activator-like effectors (TALEs) work together with the γ subunit of host transcription issue IIA (TFIIAγ) to activate the transcription of host illness susceptibility genes.
Functional TFIIA is a ternary advanced comprising α, β and γ subunits. However, whether or not TALEs recruit TFIIAα, TFIIAβ, or each stays unknown. The underlying molecular mechanisms by which TALEs mediate host susceptibility gene activation require full elucidation. Here, we present that TALEs work together with the α+γ binary subcomplex however not the α+β+γ ternary advanced of rice TFIIA (holo-OsTFIIA). The transcription issue binding (TFB) areas of TALEs, that are extremely conserved in Xanthomonas species, have a dominant function in these interactions.
Furthermore, the interplay between TALEs and the α+γ advanced displays sturdy DNA binding exercise in vitro. These outcomes collectively reveal that TALE-carrying pathogens hijack the host basal transcription components TFIIAα and TFIIAγ, however not TFIIAβ, to reinforce host susceptibility throughout pathogen an infection. The uncovered mechanism widens new insights on host-microbe interplay and present an relevant technique to breed high-resistance crop varieties.
A Conserved Basal Transcription Factor Is Required for the Function of Diverse TAL Effectors in Multiple Plant Hosts.
Many Xanthomonas micro organism use transcription activator-like effector (TALE) proteins to activate plant illness susceptibility (S) genes, and this activation contributes to illness. We not too long ago reported that rice basal transcription issue IIA gamma subunit, OsTFIIAγ5, is hijacked by TALE-carrying Xanthomonas oryzae infecting the crops.
However, whether or not TFIIAγs are additionally concerned in TALE-carrying Xanthomonas-caused illnesses in different crops is unknown. Here, molecular and genetic approaches had been used to research the function of TFIIAγs in different crops. We discovered that TFIIAγs are additionally utilized by TALE-carrying Xanthomonas to trigger illness in different crops.
The TALEs of Xanthomonas citri pv. citri (Xcc) inflicting canker in citrus and Xanthomonas campestris pv. vesicatoria (Xcv) inflicting bacterial spot in pepper and tomato interacted with corresponding host TFIIAγs as in rice. Transcriptionally suppressing TFIIAγ led to resistance to Xcc in citrus and Xcv in pepper and tomato. The 39th residue of OsTFIIAγ5 and citrus CsTFIIAγ is significant for TALE-dependent induction of plant S genes.
As mutated OsTFIIAγ5V 39E, CsTFIIAγV 39E, pepper CaTFIIAγV 39E, and tomato SlTFIIAγV 39E additionally didn’t work together with TALEs to forestall illness. These outcomes counsel that TALE-carrying micro organism share a standard mechanism for infecting crops. Using TFIIAγV 39E-type mutation could possibly be a normal technique for bettering resistance to TALE-carrying pathogens in crops.
The TAL Effector AvrBs3 from Xanthomonas campestris pv. vesicatoria Contains Multiple Export Signals and Can Enter Plant Cells within the Absence of the Type III Secretion Translocon.
Pathogenicity of the Gram-negative plant-pathogenic bacterium Xanthomonas campestris pv. vesicatoria depends upon a kind III secretion (T3S) system which translocates effector proteins into plant cells. Effector protein supply is managed by the T3S chaperone HpaB, which presumably escorts effector proteins to the secretion equipment.
One intensively studied effector is the transcription activator-like (TAL) effector AvrBs3, which binds to promoter sequences of plant goal genes and prompts plant gene expression. It was beforehand reported that kind III-dependent supply of AvrBs3 depends upon the N-terminal protein area. The indicators that management T3S and translocation of AvrBs3, nonetheless, haven’t but been characterised. In the current research, we present that T3S and translocation of AvrBs3 depend upon the N-terminal 10 and 50 amino acids, respectively.
Furthermore, we offer experimental proof that further indicators within the N-terminal 30 amino acids and the area between amino acids 64 and 152 promote translocation of AvrBs3 within the absence of HpaB. Unexpectedly, in vivo translocation assays revealed that AvrBs3 is delivered into plant cells even within the absence of HrpF, which is the anticipated channel-forming part of the T3S translocon within the plant plasma membrane.
 Cas9 Nuclease |
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| 310 | GeneOn | 2x40µg (2x250 pmol) | EUR 264 |
Cas9 Nuclease |
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| 312HC | GeneOn | 80 µg (500 pmol) | EUR 224 |
Cas9 Nuclease |
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| 314HC | GeneOn | 400 µg (2500 pmol) | EUR 745 |
 Nuclease P1 Antibody |
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| 20-abx300888 | Abbexa |
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Nuclease P1 Antibody |
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| 1-CSB-PA328459LA01PEU | Cusabio |
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Description: A polyclonal antibody against Nuclease P1. Recognizes Nuclease P1 from Penicillium citrinum. This antibody is Unconjugated. Tested in the following application: ELISA |
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 Cas9 Nuclease Lentiviral Vector |
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| K002 | ABM | 10 ug | EUR 154 |
 Nuclease P1 Polyclonal Antibody |
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| A64318 | EpiGentek | 100 µg | EUR 570.55 |
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Description: reagents widely cited |
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) Nuclease P1 Antibody (HRP) |
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| 20-abx300889 | Abbexa |
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) Nuclease P1 Antibody (FITC) |
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| 20-abx300890 | Abbexa |
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) Nuclease P1 Antibody (Biotin) |
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| 20-abx300891 | Abbexa |
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 Apoptosis-enhancing nuclease antibody |
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| 22725-100ul | SAB | 100ul | EUR 390 |
 Apoptosis enhancing nuclease antibody |
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| 70R-13466 | Fitzgerald | 100 ul | EUR 457 |
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Description: Affinity purified Rabbit polyclonal Apoptosis enhancing nuclease antibody |
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 Penicillium citrinum Nuclease P1 |
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| 1-CSB-YP328459PEU | Cusabio |
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Description: Recombinant Penicillium citrinum Nuclease P1 expressed in Yeast |
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Penicillium citrinum Nuclease P1 |
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| 1-CSB-EP328459PEU | Cusabio |
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Description: Recombinant Penicillium citrinum Nuclease P1 expressed in E.coli |
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Penicillium citrinum Nuclease P1 |
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| 1-CSB-EP328459PEUa0 | Cusabio |
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Description: Recombinant Penicillium citrinum Nuclease P1 expressed in E.coli |
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 anti-Apoptosis enhancing nuclease |
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| YF-PA20583 | Abfrontier | 50 ug | EUR 363 |
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Description: Mouse polyclonal to Apoptosis enhancing nuclease |
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 Antibody) Apoptosis-Enhancing Nuclease (AEN) Antibody |
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| 20-abx308819 | Abbexa |
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 Recombinant Human APEX nuclease-1 |
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| 7-02476 | CHI Scientific | 2µg | Ask for price |
Recombinant Human APEX nuclease-1 |
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| 7-02477 | CHI Scientific | 10µg | Ask for price |
Recombinant Human APEX nuclease-1 |
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| 7-02478 | CHI Scientific | 1mg | Ask for price |
) Human Apoptosis-enhancing nuclease (AEN) |
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| 1-CSB-EP819883HU | Cusabio |
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Description: Recombinant Human Apoptosis-enhancing nuclease(AEN),partial expressed in E.coli |
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 Nuclease P1 Antibody, HRP conjugated |
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| 1-CSB-PA328459LB01PEU | Cusabio |
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Description: A polyclonal antibody against Nuclease P1. Recognizes Nuclease P1 from Penicillium citrinum. This antibody is HRP conjugated. Tested in the following application: ELISA |
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 Nuclease P1 Antibody, FITC conjugated |
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| 1-CSB-PA328459LC01PEU | Cusabio |
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Description: A polyclonal antibody against Nuclease P1. Recognizes Nuclease P1 from Penicillium citrinum. This antibody is FITC conjugated. Tested in the following application: ELISA |
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 Nuclease P1 Antibody, Biotin conjugated |
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| 1-CSB-PA328459LD01PEU | Cusabio |
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Description: A polyclonal antibody against Nuclease P1. Recognizes Nuclease P1 from Penicillium citrinum. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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) IPTG, Animal-Free (Dioxane-Free) |
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| 1649-1G | Biovision | EUR 115 | |
IPTG, Animal-Free (Dioxane-Free) |
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| 1649-50G | Biovision | EUR 985 | |
IPTG, Animal-Free (Dioxane-Free) |
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| 1649-5G | Biovision | EUR 218 | |
) Block-Free ELISA Reagent (Protein-Free) |
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| M4101-250 | Biovision | EUR 457 | |
Block-Free ELISA Reagent (Protein-Free) |
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| M4101-50 | Biovision | EUR 153 | |
) Rabbit Reticulocyte Lysate System (Nuclease treated) |
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| 20-abx800017 | Abbexa |
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 Antibody) Fanconi-Associated Nuclease 1 (FAN1) Antibody |
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| 20-abx113962 | Abbexa |
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 Nuclease P1 Polyclonal Antibody, HRP Conjugated |
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| A64319 | EpiGentek | 100 µg | EUR 570.55 |
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Description: Ask the seller for details |
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 Nuclease P1 Polyclonal Antibody, FITC Conjugated |
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| A64320 | EpiGentek | 100 µg | EUR 570.55 |
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Description: The best epigenetics products |
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 Nuclease P1 Polyclonal Antibody, Biotin Conjugated |
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| A64321 | EpiGentek | 100 µg | EUR 570.55 |
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Description: kits suitable for this type of research |
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 Antibody (HRP)) Apoptosis-Enhancing Nuclease (AEN) Antibody (HRP) |
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| 20-abx308820 | Abbexa |
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 Antibody (FITC)) Apoptosis-Enhancing Nuclease (AEN) Antibody (FITC) |
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| 20-abx308821 | Abbexa |
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 Antibody (Biotin)) Apoptosis-Enhancing Nuclease (AEN) Antibody (Biotin) |
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| 20-abx308822 | Abbexa |
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 Cas9 Nuclease - 80µg - 1,600 ng/µl |
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| 3273-(HC) | Intact Genomics | 1/EA | EUR 189 |
 Cas9 Nuclease - 400µg - 1,600 ng/µl |
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| 3276-(HC) | Intact Genomics | 1/EA | EUR 565 |
 GeneArt CRISPR Nuclease Vector- OFP- gRNA |
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| PVT10418 | Lifescience Market | 2 ug | EUR 301 |
 Free-T3/ Rat Free- T3 ELISA Kit |
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| ELA-E0450r | Lifescience Market | 96 Tests | EUR 886 |
 VitroPlus III, Serum-Free, Xeno-Free, Complete |
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| PC00B2 | Neuromics | 500 ml | EUR 375 |
 ELISA kit) Goat Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E06A1296-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A sandwich ELISA for quantitative measurement of Goat Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E06A1296-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A sandwich ELISA for quantitative measurement of Goat Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E06A1296-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A sandwich ELISA for quantitative measurement of Goat Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 ELISA kit) Rat Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E02A1296-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A sandwich ELISA for quantitative measurement of Rat Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E02A1296-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A sandwich ELISA for quantitative measurement of Rat Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E02A1296-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A sandwich ELISA for quantitative measurement of Rat Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 ELISA kit) Mouse Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E03A1296-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E03A1296-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E03A1296-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 ELISA kit) Rabbit Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E04A1296-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A sandwich ELISA for quantitative measurement of Rabbit Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E04A1296-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A sandwich ELISA for quantitative measurement of Rabbit Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E04A1296-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A sandwich ELISA for quantitative measurement of Rabbit Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 ELISA kit) Human Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E01A1296-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A sandwich ELISA for quantitative measurement of Human Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E01A1296-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A sandwich ELISA for quantitative measurement of Human Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E01A1296-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A sandwich ELISA for quantitative measurement of Human Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 ELISA kit) Pig Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E07A1296-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A sandwich ELISA for quantitative measurement of Porcine Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E07A1296-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A sandwich ELISA for quantitative measurement of Porcine Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E07A1296-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A sandwich ELISA for quantitative measurement of Porcine Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 ELISA kit) Monkey Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E09A1296-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A sandwich ELISA for quantitative measurement of Monkey Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Monkey Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E09A1296-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A sandwich ELISA for quantitative measurement of Monkey Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Monkey Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E09A1296-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A sandwich ELISA for quantitative measurement of Monkey Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 ELISA kit) Dog Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E08A1296-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A sandwich ELISA for quantitative measurement of Canine Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E08A1296-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A sandwich ELISA for quantitative measurement of Canine Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Apoptosis enhancing nuclease(AEN) ELISA kit |
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| E08A1296-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A sandwich ELISA for quantitative measurement of Canine Apoptosis enhancing nuclease(AEN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Human Apoptosis- enhancing nuclease, AEN ELISA KIT |
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| ELI-24139h | Lifescience Market | 96 Tests | EUR 824 |
 Human Putative nuclease HARBI1, HARBI1 ELISA KIT |
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| ELI-08812h | Lifescience Market | 96 Tests | EUR 824 |
 Mouse Nuclease EXOG, mitochondrial, Exog ELISA KIT |
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| ELI-09274m | Lifescience Market | 96 Tests | EUR 865 |
 Mouse Putative nuclease HARBI1, Harbi1 ELISA KIT |
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| ELI-27736m | Lifescience Market | 96 Tests | EUR 865 |
 Mouse Apoptosis- enhancing nuclease, Aen ELISA KIT |
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| ELI-34824m | Lifescience Market | 96 Tests | EUR 865 |
 Bovine Putative nuclease HARBI1, HARBI1 ELISA KIT |
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| ELI-30865b | Lifescience Market | 96 Tests | EUR 928 |
 Human Nuclease EXOG, mitochondrial, EXOG ELISA KIT |
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| ELI-31367h | Lifescience Market | 96 Tests | EUR 824 |
 ELISA Kit) Human Apoptosis Enhancing Nuclease (AEN) ELISA Kit |
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| abx384594-96tests | Abbexa | 96 tests | EUR 911 |
|
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 ELISA Kit) Human Putative Nuclease HARBI1 (HARBI1) ELISA Kit |
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| abx384989-96tests | Abbexa | 96 tests | EUR 911 |
|
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 ELISA Kit) Human Nuclease EXOG, Mitochondrial (EXOG) ELISA Kit |
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| abx387218-96tests | Abbexa | 96 tests | EUR 911 |
|
|||
 ELISA Kit) Mouse Apoptosis Enhancing Nuclease (AEN) ELISA Kit |
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| abx388598-96tests | Abbexa | 96 tests | EUR 911 |
|
|||
 ELISA Kit) Mouse Putative Nuclease HARBI1 (HARBI1) ELISA Kit |
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| abx389495-96tests | Abbexa | 96 tests | EUR 911 |
|
|||
 ELISA Kit) Mouse Nuclease EXOG, Mitochondrial (EXOG) ELISA Kit |
|||
| abx390090-96tests | Abbexa | 96 tests | EUR 911 |
|
|||
 ELISA Kit) Rat Apoptosis Enhancing Nuclease (AEN) ELISA Kit |
|||
| abx390985-96tests | Abbexa | 96 tests | EUR 911 |
|
|||
 ELISA Kit) Rat Putative Nuclease HARBI1 (HARBI1) ELISA Kit |
|||
| abx391430-96tests | Abbexa | 96 tests | EUR 911 |
|
|||
 ELISA Kit) Human APEX Nuclease 1 (APEX1) ELISA Kit |
|||
| DLR-APEX1-Hu-48T | DL Develop | 48T | EUR 517 |
|
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Description: A sandwich quantitative ELISA assay kit for detection of Human APEX Nuclease 1 (APEX1) in samples from tissue homogenates, cell lysates or other biological fluids. |
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Human APEX Nuclease 1 (APEX1) ELISA Kit |
|||
| DLR-APEX1-Hu-96T | DL Develop | 96T | EUR 673 |
|
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Description: A sandwich quantitative ELISA assay kit for detection of Human APEX Nuclease 1 (APEX1) in samples from tissue homogenates, cell lysates or other biological fluids. |
|||
 ELISA Kit) Mouse APEX Nuclease 1 (APEX1) ELISA Kit |
|||
| DLR-APEX1-Mu-48T | DL Develop | 48T | EUR 527 |
|
|||
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Description: A sandwich quantitative ELISA assay kit for detection of Mouse APEX Nuclease 1 (APEX1) in samples from tissue homogenates, cell lysates or other biological fluids. |
|||
Mouse APEX Nuclease 1 (APEX1) ELISA Kit |
|||
| DLR-APEX1-Mu-96T | DL Develop | 96T | EUR 688 |
|
|||
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse APEX Nuclease 1 (APEX1) in samples from tissue homogenates, cell lysates or other biological fluids. |
|||
 ELISA Kit) Rat APEX Nuclease 1 (APEX1) ELISA Kit |
|||
| DLR-APEX1-Ra-48T | DL Develop | 48T | EUR 549 |
|
|||
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat APEX Nuclease 1 (APEX1) in samples from tissue homogenates, cell lysates or other biological fluids. |
|||
Rat APEX Nuclease 1 (APEX1) ELISA Kit |
|||
| DLR-APEX1-Ra-96T | DL Develop | 96T | EUR 718 |
|
|||
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat APEX Nuclease 1 (APEX1) in samples from tissue homogenates, cell lysates or other biological fluids. |
|||
) Bacillus subtilis Sporulation-specific extracellular nuclease (nucB) |
|||
| 1-CSB-YP337282BRJ | Cusabio |
|
|
|
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Description: Recombinant Bacillus subtilis Sporulation-specific extracellular nuclease(nucB) expressed in Yeast |
|||
 APEX1 APEX Nuclease-1 Human Recombinant Protein |
|||
| PROTP27695 | BosterBio | Regular: 10ug | EUR 317 |
|
Description: APEX1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 332 amino acids (1-318a.a.) and having a molecular mass of 36.9kDa.;APEX1 protein is fused to a 14 amino acid T7-tag at N-terminus and is purified by standard chromatography. |
|||
Human APEX Nuclease 1 (APEX1) ELISA Kit |
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| RD-APEX1-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 521 |
Human APEX Nuclease 1 (APEX1) ELISA Kit |
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| RD-APEX1-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 723 |
Mouse APEX Nuclease 1 (APEX1) ELISA Kit |
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| RD-APEX1-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 533 |
Mouse APEX Nuclease 1 (APEX1) ELISA Kit |
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| RD-APEX1-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 740 |
Rat APEX Nuclease 1 (APEX1) ELISA Kit |
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| RD-APEX1-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 557 |
Rat APEX Nuclease 1 (APEX1) ELISA Kit |
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| RD-APEX1-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 775 |
Human APEX Nuclease 1 (APEX1) ELISA Kit |
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| RDR-APEX1-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 544 |
Human APEX Nuclease 1 (APEX1) ELISA Kit |
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| RDR-APEX1-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 756 |
Mouse APEX Nuclease 1 (APEX1) ELISA Kit |
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| RDR-APEX1-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 557 |
Mouse APEX Nuclease 1 (APEX1) ELISA Kit |
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| RDR-APEX1-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 774 |
Rat APEX Nuclease 1 (APEX1) ELISA Kit |
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| RDR-APEX1-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 583 |
Rat APEX Nuclease 1 (APEX1) ELISA Kit |
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| RDR-APEX1-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 811 |
ELISA Kit) Human APEX Nuclease 2(APEX2)ELISA Kit |
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| QY-E05142 | Qayee Biotechnology | 96T | EUR 361 |
ELISA Kit) Human APEX Nuclease 1(APEX1)ELISA Kit |
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| QY-E05143 | Qayee Biotechnology | 96T | EUR 361 |
 ELISA Kit) Canine Free Tri-iodothyronine(Free-T3) ELISA Kit |
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| CSB-E13195c-24T | Cusabio | 1 plate of 24 wells | EUR 165 |
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Description: Quantitative competitive ELISA kit for measuring Canine Free Tri-iodothyronine (Free-T3) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Canine Free Tri-iodothyronine(Free-T3) ELISA Kit |
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| 1-CSB-E13195c | Cusabio |
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Description: Quantitative competitive ELISA kit for measuring Canine Free Tri-iodothyronine(Free-T3) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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 Human Free Tri-iodothyronine, Free-T3 ELISA Kit |
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| CSB-E05075h-24T | Cusabio | 1 plate of 24 wells | EUR 165 |
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Description: Quantitativesandwich ELISA kit for measuring Human Free Tri-iodothyronine, Free-T3 in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Human Free Tri-iodothyronine, Free-T3 ELISA Kit |
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| 1-CSB-E05075h | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Human Free Tri-iodothyronine, Free-T3 in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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 Rat Free Tri-iodothyronine, Free-T3 ELISA Kit |
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| CSB-E05076r-24T | Cusabio | 1 plate of 24 wells | EUR 165 |
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Description: Quantitative competitive ELISA kit for measuring Rat Free Tri-iodothyronine, Free-T3 in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Rat Free Tri-iodothyronine, Free-T3 ELISA Kit |
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| 1-CSB-E05076r | Cusabio |
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Description: Quantitative competitive ELISA kit for measuring Rat Free Tri-iodothyronine, Free-T3 in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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 Mouse Free Tri-iodothyronine, Free-T3 ELISA Kit |
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| CSB-E05077m-24T | Cusabio | 1 plate of 24 wells | EUR 165 |
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Description: Quantitative competitive ELISA kit for measuring Mouse Free Tri-iodothyronine, Free-T3 in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Mouse Free Tri-iodothyronine, Free-T3 ELISA Kit |
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| 1-CSB-E05077m | Cusabio |
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Description: Quantitative competitive ELISA kit for measuring Mouse Free Tri-iodothyronine, Free-T3 in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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 BSA Endotoxin Free |
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| AK8917-0100 | Akron Biotech | 100g | Ask for price |
BSA Endotoxin Free |
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| AK8917-0500 | Akron Biotech | 500g | Ask for price |
BSA Endotoxin Free |
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| AK8917-1000 | Akron Biotech | 1kg | Ask for price |
) Carubicin (Free base) |
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| B1853-1 | Biovision | EUR 153 | |
Carubicin (Free base) |
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| B1853-5 | Biovision | EUR 457 | |
) FIPI (free base) |
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| B2372-25 | Biovision | EUR 631 | |
FIPI (free base) |
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| B2372-5 | Biovision | EUR 196 | |
) Terbinafine (Free base) |
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| B2423-250 | Biovision | EUR 207 | |
Terbinafine (Free base) |
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| B2423-50 | Biovision | EUR 120 | |
 A23187, free acid |
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| B6646-10 | ApexBio | 10 mg | EUR 171 |
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Description: A23187, free acid is a Ca2+ ionophore [1]. Ca2+ ionophore acts as a Ca2+ ionophore, allowing Ca2+ to cross cell membranes. A23187, free acid is a Ca2+ ionophore. |
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A23187, free acid |
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| B6646-25 | ApexBio | 25 mg | EUR 318 |
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Description: A23187, free acid is a Ca2+ ionophore [1]. Ca2+ ionophore acts as a Ca2+ ionophore, allowing Ca2+ to cross cell membranes. A23187, free acid is a Ca2+ ionophore. |
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A23187, free acid |
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| B6646-5 | ApexBio | 5 mg | EUR 141 |
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Description: A23187, free acid is a Ca2+ ionophore [1]. Ca2+ ionophore acts as a Ca2+ ionophore, allowing Ca2+ to cross cell membranes. A23187, free acid is a Ca2+ ionophore. |
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 Ionomycin free acid |
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| B6947-10 | ApexBio | 10 mg | EUR 438 |
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Description: Ionomycin is a selective and potent calcium ionophore, which acts as a motile Ca2+ carrier.by direct stimulation of store-regulated cation entry across biological membranes, ionomycin can effectively enhance Ca2+ influx. |
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Ionomycin free acid |
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| B6947-25 | ApexBio | 25 mg | EUR 805 |
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Description: Ionomycin is a selective and potent calcium ionophore, which acts as a motile Ca2+ carrier.by direct stimulation of store-regulated cation entry across biological membranes, ionomycin can effectively enhance Ca2+ influx. |
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Ionomycin free acid |
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| B6947-5 | ApexBio | 5 mg | EUR 254 |
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Description: Ionomycin is a selective and potent calcium ionophore, which acts as a motile Ca2+ carrier.by direct stimulation of store-regulated cation entry across biological membranes, ionomycin can effectively enhance Ca2+ influx. |
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) MCC950 (Free base) |
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| B1031-1 | Biovision | EUR 153 | |
MCC950 (Free base) |
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| B1031-5 | Biovision | EUR 457 | |
) Apatinib (Free base) |
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| B1613-25 | Biovision | EUR 414 | |
Apatinib (Free base) |
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| B1613-5 | Biovision | EUR 142 | |
 Cefpodoxime Free Acid |
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| C016-100MG | TOKU-E | 100 mg | EUR 229 |
 Ceftriaxone free acid |
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| C074-1G | TOKU-E | 1 g | EUR 184 |
Ceftriaxone free acid |
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| C074-250MG | TOKU-E | 250 mg | EUR 106 |
 Cefmetazole free acid |
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| C122-1G | TOKU-E | 1g | EUR 102 |
Cefmetazole free acid |
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| C122-5G | TOKU-E | 5g | EUR 271 |
) Cefpodoxime (free acid) |
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| C3052-100 | ApexBio | 100 mg | EUR 290 |
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Description: Cefpodoxime, as known as R 3763, is a metabolite of cefpodoxime proxetil. It is demonstrated that cefpodoxime, as an oral third generation cephalosporin antibiotic, is active against most Gram-positive and Gram-negative bacteria. |
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Cefpodoxime (free acid) |
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| C3052-25 | ApexBio | 25 mg | EUR 123 |
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Description: Cefpodoxime, as known as R 3763, is a metabolite of cefpodoxime proxetil. It is demonstrated that cefpodoxime, as an oral third generation cephalosporin antibiotic, is active against most Gram-positive and Gram-negative bacteria. |
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Cefpodoxime (free acid) |
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| C3052-50 | ApexBio | 50 mg | EUR 187 |
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Description: Cefpodoxime, as known as R 3763, is a metabolite of cefpodoxime proxetil. It is demonstrated that cefpodoxime, as an oral third generation cephalosporin antibiotic, is active against most Gram-positive and Gram-negative bacteria. |
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 AZD4547, Free Base |
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| ADC-P-063 | Creative Biolabs | unit | Ask for price |
 AZD8055, Free Base |
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| ADC-P-064 | Creative Biolabs | unit | Ask for price |
 Cyclopamine, Free Base |
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| ADC-P-079 | Creative Biolabs | unit | Ask for price |
 Ixabepilone, Free Base |
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| ADC-P-104 | Creative Biolabs | unit | Ask for price |
) R406(free base) |
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| E1KS1533 | EnoGene | 2mg | EUR 521 |
 free-PSA Antigen |
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| E62C00101 | EnoGene | 20ug | EUR 382 |
 RPR107393 free base |
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| HY-100299 | MedChemExpress | 1mg | EUR 481 |
 FR167344 free base |
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| HY-100301 | MedChemExpress | 1mg | EUR 2637 |
 FR183998 free base |
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| HY-100302 | MedChemExpress | 1mg | EUR 1127 |
 FR194738 free base |
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| HY-100303 | MedChemExpress | 1mg | EUR 1990 |
) MK591 (free acid) |
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| HY-10037 | MedChemExpress | 5mg | EUR 229 |
) Vatalanib (free base) |
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| HY-10203 | MedChemExpress | 5mg | EUR 119 |
The presence of HpaB- and HrpF-independent transport routes means that the supply of AvrBs3 is initiated throughout early phases of the an infection course of, presumably earlier than the activation of HpaB or the insertion of the translocon into the plant plasma membrane.