Monday, 02 October, 2023

Tal Effectors

Transcription activator-like effector nuclease

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  • Non-TAL Effectors From Xanthomonas oryzae pv. oryzae Suppress Peptidoglycan-Triggered MAPK Activation in Rice.
Non-TAL Effectors From Xanthomonas oryzae pv. oryzae Suppress Peptidoglycan-Triggered MAPK Activation in Rice.
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Non-TAL Effectors From Xanthomonas oryzae pv. oryzae Suppress Peptidoglycan-Triggered MAPK Activation in Rice.

Xanthomonas oryzae pv. oryzae, the causal pathogen of bacterial blight of rice, depends upon its sort III secretion system and related effector proteins to develop and colonize the vascular tissues of rice crops. The sort III effectors embrace a household of intently associated transcription activator-like (TAL) effectors and the remainder of various effectors, so-called non-TAL effectors. Our understanding of non-TAL effectors for pathogenesis in rice blight continues to be restricted.
Here we report a possible methodology to quickly detect the activation of mitogen-activated protein kinase pathway in rice mesophyll protoplasts by the Xoryzae pv. oryzae derived peptidoglycan and display screen for virulent effectors that may suppress the pathogen-associated molecular sample triggered immunity (PTI) response.
Amongst 17 non-TAL effectors transiently expressed in rice cells, we discovered that three effectors (XopZ, XopN, and XopV) have been capable of suppress the peptidoglycan-triggered MAPK activation. The triple mutant of the X. oryzae pv. oryzae pressure PXO99A missing XopZXopN, and XopV confirmed additively decreased virulence. Adding again both of genes restored the virulence of the triple mutant. Our outcomes exhibit the collective and redundant capability of protection suppression by non-TAL effectors in inflicting bacterial blight of rice.

 A Simple TAL Effector Assembly Reaction Using Isothermal Assembly.

Transcription activator-like effectors (TALEs) comprise programmable DNA-binding domains that may be fused to numerous effectors to control genetic sequences or transcriptional state. However, the development of plasmids encoding the modular DNA-binding area stays difficult as a consequence of their repetitive nature. Here, we describe strategies for a easy TALE meeting response (STAR) that makes use of a 68-part plasmid library to create TALEs binding to 17 bp goal sequences.
Manual manufacturing of many tens of TALEs may be achieved utilizing a easy eight h protocol, with full size sequence-verified plasmids obtainable inside just a few days. This easy story meeting response (STAR) offers a handy methodology for producing tens to tons of of TALENs or TALE-TFs with out the necessity for giant plasmid libraries or costly liquid dealing with.

Efficient enrichment cloning of TAL effector genes from Xanthomonas.

Many plant-pathogenic xanthomonads use a sort III secretion system to translocate Transcription Activator-Like (TAL) effectors into eukaryotic host cells the place they act as transcription components. Target genes are induced upon binding of a TAL effector to double-stranded DNA in a sequence-specific method. DNA binding is ruled by a extremely repetitive protein area, which consists of an array of almost equivalent repeats of ca. 102 base pairs.
Many species and pathovars of Xanthomonas, together with pathogens of rice, cereals, cassava, citrus and cotton, encode a number of TAL effectors in their genomes. Some of the TAL effectors have been proven to behave as key pathogenicity components, which induce the expression of susceptibility genes to the advantage of the pathogen. However, as a result of repetitive character and the presence of a number of gene copies, high-throughput cloning of TAL effector genes stays a problem.
Non-TAL Effectors From Xanthomonas oryzae pv. oryzae Suppress Peptidoglycan-Triggered MAPK Activation in Rice.
In order to isolate full TAL effector gene repertoires, we developed an enrichment cloning technique based mostly on •genome-informed in silico optimization of restriction digestions,•selective restriction digestion of genomic DNA, and•measurement fractionation of DNA fragments. Our fast, low-cost and highly effective methodology permits environment friendly cloning of TAL effector genes from xanthomonads, as demonstrated for 2 rice-pathogenic strains of Xanthomonas oryzae from Africa.

Ectopic expression of the TAL effector AvrXa7 in Xanthomonas citri subsp. citri hinders citrus canker symptom formation by modulating transcriptional profile of citrus genes.

Xanthomonas citri subsp. citri (Xcc) is the causal agent of citrus canker, a severe bacterial illness that impacts citrus bushes worldwide. The ectopic expression of TAL effector AvrXa7 in Xcc suppressed canker improvement. The Xcc pressure expressing avrXa7 induced a yellow symptom across the inoculation website. Transcriptome evaluation revealed 315 differentially expressed genes, which have been categorized into a number of practical teams.
click for more: Mouse Versican (VCAN) Protein Reconstitute to the original concentration in ddH2O. If further dilutions are required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0, to a concentration of 0.1-1.0 mg/ml. Do not vortex.
The extra fascinating genes have been these concerned in the biosynthesis of terpene and ethylene. In specific, the linoleate 13 S-lipoxygenase gene CsLOX2-1 was discovered to own the AvrXa7 binding sequence in the promoter area. The recognition of AvrXa7 to the CsLOX2-1 promoter was subsequently confirmed by yeast one-hybrid and electrophoretic mobility shift experiments. This demonstrated that the TALE effector AvrXa7 promotes CsLOX2-1 expression by immediately binding to the promoter sequence. Our findings contribute a worthwhile clue to figuring out the potential genes that can be utilized to stop citrus canker.

Two ancestral genes formed the Xanthomonas campestris TAL effector gene repertoire.

Xanthomonas transcription activator-like effectors (TALEs) are injected inside plant cells to advertise host susceptibility by enhancing transcription of host susceptibility genes. TALE-encoding (tal) genes have been considered absent from Brassicaceae-infecting Xanthomonas campestris (Xc) genomes based mostly on 4 reference genomic sequences. We found tal genes in 26 of 49 Xc strains remoted worldwide and used a mixture of single molecule actual time (SMRT) and tal amplicon sequencing to yield a near-complete description of the TALEs discovered in Xc (Xc TALome).
The 53 sequenced tal genes encode 21 distinct DNA binding domains that kind into seven main DNA binding specificities. In silico evaluation of the Brassica rapa promoterome recognized a repertoire of predicted TALE targets, 5 of which have been experimentally validated utilizing quantitative reverse transcription polymerase chain response.

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 647

A6-686-C100 ExBio 0.1 mg 322.8 EUR

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 647

A6-730-C100 ExBio 0.1 mg 322.8 EUR

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 647

A6-737-C100 ExBio 0.1 mg 322.8 EUR

XFD647 maleimide *C2, XFD647 Same Structure to Alexa Fluor™ 647*

1895 AAT Bioquest 1 mg 222 EUR

SAM FCM (Alexa Fluor 488)

abx098904-60tests Abbexa 60 tests 1629.6 EUR

Endoglin/CD105 Alexa Fluor

FC15024 Neuromics 100 Tests 537.6 EUR

XFD647 NHS Ester *Same Structure to Alexa Fluor™ 647 NHS Ester*

1833 AAT Bioquest 1 mg 222 EUR

XFD647 NHS Ester *Same Structure to Alexa Fluor™ 647 NHS Ester*

71909 AAT Bioquest 5 mg 781 EUR

EGFR antibody (Alexa Fluor 488)

61R-E109BAF Fitzgerald 125 ug 847.2 EUR
Description: Mouse monoclonal EGFR antibody (Alexa Fluor 488)

Anti-RPSA Alexa Fluor® 488

A4-829-C100 ExBio 0.1 mg 372 EUR

Goat anti Mouse IgG1 (Alexa Fluor 488)

43R-1649 Fitzgerald 500 ug 684 EUR
Description: Goat anti Mouse IgG1 secondary antibody (Alexa Fluor 488)

XFD647 Anti-human CD3 Antibody *SK7, XFD647 Same Structure to Alexa Fluor™ 647*

10033180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD3 Antibody *SK7, XFD647 Same Structure to Alexa Fluor™ 647*

10033181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD4 Antibody *SK3, XFD647 Same Structure to Alexa Fluor™ 647*

10042180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD4 Antibody *SK3, XFD647 Same Structure to Alexa Fluor™ 647*

10042181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD8 Antibody *SK1, XFD647 Same Structure to Alexa Fluor™ 647*

10081180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD8 Antibody *SK1, XFD647 Same Structure to Alexa Fluor™ 647*

10081181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD28 Antibody *9.3, XFD647 Same Structure to Alexa Fluor™ 647*

10281180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD28 Antibody *9.3, XFD647 Same Structure to Alexa Fluor™ 647*

10281181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD64 Antibody *10.1, XFD647 Same Structure to Alexa Fluor™ 647*

10640180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD64 Antibody *10.1, XFD647 Same Structure to Alexa Fluor™ 647*

10640181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD4 Antibody *SK3, XFD647 Same Structure to Alexa Fluor™ 647*

10042180-100tests AAT Bioquest 100 tests 245 EUR
Description: SK3 is an anti-human monoclonal antibody that recognizes the CD4 antigen.

XFD647 Anti-human CD4 Antibody *SK3, XFD647 Same Structure to Alexa Fluor™ 647*

10042181-500tests AAT Bioquest 500 tests 918 EUR
Description: SK3 is an anti-human monoclonal antibody that recognizes the CD4 antigen.

XFD647 Anti-human CD8 Antibody *SK1, XFD647 Same Structure to Alexa Fluor™ 647*

10081180-100tests AAT Bioquest 100 tests 245 EUR
Description: SK1 is an anti-human monoclonal antibody that is specific for the CD8a antigen.

XFD647 Anti-human CD8 Antibody *SK1, XFD647 Same Structure to Alexa Fluor™ 647*

10081181-500tests AAT Bioquest 500 tests 918 EUR
Description: SK1 is an anti-human monoclonal antibody that is specific for the CD8a antigen.

XFD647 Anti-human CD3 Antibody *SK7, XFD647 Same Structure to Alexa Fluor™ 647*

10033180-100tests AAT Bioquest 100 tests 245 EUR
Description: The SK7 monoclonal antibody reacts with human CD3e, a 20 kD member of the Ig superfamily often found on the surface of t cells, tregs and nkt cells.

XFD647 Anti-human CD3 Antibody *SK7, XFD647 Same Structure to Alexa Fluor™ 647*

10033181-500tests AAT Bioquest 500 tests 918 EUR
Description: The SK7 monoclonal antibody reacts with human CD3e, a 20 kD member of the Ig superfamily often found on the surface of t cells, tregs and nkt cells.

XFD647 Anti-human CD64 Antibody *10.1, XFD647 Same Structure to Alexa Fluor™ 647*

10640180-100tests AAT Bioquest 100 tests 245 EUR
Description: The 10.1 monoclonal antibody binds with human CD64, a 72 kD single-pass type i membrane protein typically expressed on the surface of granulocytes, monocytes and dendritic cells.

XFD647 Anti-human CD64 Antibody *10.1, XFD647 Same Structure to Alexa Fluor™ 647*

10640181-500tests AAT Bioquest 500 tests 918 EUR
Description: The 10.1 monoclonal antibody binds with human CD64, a 72 kD single-pass type i membrane protein typically expressed on the surface of granulocytes, monocytes and dendritic cells.

XFD647 Anti-human CD28 Antibody *9.3, XFD647 Same Structure to Alexa Fluor™ 647*

10281180-100tests AAT Bioquest 100 tests 245 EUR
Description: The 9.3 monoclonal antibody binds with human CD28, a 44 kD transmembrane glycoprotein typically located on the surface of natural killer cells and plasma cells.

XFD647 Anti-human CD28 Antibody *9.3, XFD647 Same Structure to Alexa Fluor™ 647*

10281181-500tests AAT Bioquest 500 tests 918 EUR
Description: The 9.3 monoclonal antibody binds with human CD28, a 44 kD transmembrane glycoprotein typically located on the surface of natural killer cells and plasma cells.

XFD647 Anti-human CD11c Antibody *3.9, XFD647 Same Structure to Alexa Fluor™ 647*

10113180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD11c Antibody *3.9, XFD647 Same Structure to Alexa Fluor™ 647*

10113181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD1 Antibody *SN13, XFD647 Same Structure to Alexa Fluor™ 647*

10012170 AAT Bioquest 100 tests 547 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD1 Antibody *SN13, XFD647 Same Structure to Alexa Fluor™ 647*

10012171 AAT Bioquest 500 tests 2051 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD1 Antibody *L161, XFD647 Same Structure to Alexa Fluor™ 647*

10013170 AAT Bioquest 100 tests 547 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD1 Antibody *L161, XFD647 Same Structure to Alexa Fluor™ 647*

10013171 AAT Bioquest 500 tests 2051 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD9 Antibody *HI9a, XFD647 Same Structure to Alexa Fluor™ 647*

10090180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD9 Antibody *HI9a, XFD647 Same Structure to Alexa Fluor™ 647*

10090181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD7 Antibody *HIT7, XFD647 Same Structure to Alexa Fluor™ 647*

10070180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD7 Antibody *HIT7, XFD647 Same Structure to Alexa Fluor™ 647*

10070181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD16 Antibody *3G8, XFD647 Same Structure to Alexa Fluor™ 647*

10161180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD16 Antibody *3G8, XFD647 Same Structure to Alexa Fluor™ 647*

10161181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD19 Antibody *4G7, XFD647 Same Structure to Alexa Fluor™ 647*

10193180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD19 Antibody *4G7, XFD647 Same Structure to Alexa Fluor™ 647*

10193181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-mouse CD19 Antibody *1D3, XFD647 Same Structure to Alexa Fluor™ 647*

10194170 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-mouse CD19 Antibody *1D3, XFD647 Same Structure to Alexa Fluor™ 647*

10194171 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD38 Antibody *HB7, XFD647 Same Structure to Alexa Fluor™ 647*

10382170 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD38 Antibody *HB7, XFD647 Same Structure to Alexa Fluor™ 647*

10382171 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD40 Antibody *G28.5, XFD647 Same Structure to Alexa Fluor™ 647*

10401180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD40 Antibody *G28.5, XFD647 Same Structure to Alexa Fluor™ 647*

10401181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD32 Antibody *3D3, XFD647 Same Structure to Alexa Fluor™ 647*

10321180 AAT Bioquest 100 tests 547 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD32 Antibody *3D3, XFD647 Same Structure to Alexa Fluor™ 647*

10321181 AAT Bioquest 500 tests 2051 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD45 Antibody *2D1, XFD647 Same Structure to Alexa Fluor™ 647*

10454180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD45 Antibody *2D1, XFD647 Same Structure to Alexa Fluor™ 647*

10454181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD72 Antibody *3F3, XFD647 Same Structure to Alexa Fluor™ 647*

10720180 AAT Bioquest 100 tests 547 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD72 Antibody *3F3, XFD647 Same Structure to Alexa Fluor™ 647*

10720181 AAT Bioquest 500 tests 2051 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD73 Antibody *AD2, XFD647 Same Structure to Alexa Fluor™ 647*

10730180 AAT Bioquest 100 tests 547 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD73 Antibody *AD2, XFD647 Same Structure to Alexa Fluor™ 647*

10730181 AAT Bioquest 500 tests 2051 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD82 Antibody *C33, XFD647 Same Structure to Alexa Fluor™ 647*

10820180 AAT Bioquest 100 tests 547 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD82 Antibody *C33, XFD647 Same Structure to Alexa Fluor™ 647*

10820181 AAT Bioquest 500 tests 2051 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD111 Antibody *R1.302, XFD647 Same Structure to Alexa Fluor™ 647*

11110170 AAT Bioquest 100 tests 547 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD111 Antibody *R1.302, XFD647 Same Structure to Alexa Fluor™ 647*

11110171 AAT Bioquest 500 tests 2051 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD112 Antibody *R2.525, XFD647 Same Structure to Alexa Fluor™ 647*

11120170 AAT Bioquest 100 tests 547 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD112 Antibody *R2.525, XFD647 Same Structure to Alexa Fluor™ 647*

11120171 AAT Bioquest 500 tests 2051 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD7 Antibody *HIT7, XFD647 Same Structure to Alexa Fluor™ 647*

10070180-100tests AAT Bioquest 100 tests 245 EUR
Description: HIT7 is an anti-human monoclonal antibody that recognizes the CD7 antigen.

XFD647 Anti-human CD7 Antibody *HIT7, XFD647 Same Structure to Alexa Fluor™ 647*

10070181-500tests AAT Bioquest 500 tests 918 EUR
Description: HIT7 is an anti-human monoclonal antibody that recognizes the CD7 antigen.

XFD647 Anti-human CD9 Antibody *HI9a, XFD647 Same Structure to Alexa Fluor™ 647*

10090180-100tests AAT Bioquest 100 tests 245 EUR
Description: HI9a is an anti-human monoclonal antibody that recognizes the CD9 antigen.

XFD647 Anti-human CD9 Antibody *HI9a, XFD647 Same Structure to Alexa Fluor™ 647*

10090181-500tests AAT Bioquest 500 tests 918 EUR
Description: HI9a is an anti-human monoclonal antibody that recognizes the CD9 antigen.

XFD647 Anti-human CD11c Antibody *3.9, XFD647 Same Structure to Alexa Fluor™ 647*

10113180-100tests AAT Bioquest 100 tests 245 EUR
Description: 3.9 is an anti-human monoclonal antibody that forms an immune complex with the CD11c antigen.

XFD647 Anti-human CD11c Antibody *3.9, XFD647 Same Structure to Alexa Fluor™ 647*

10113181-500tests AAT Bioquest 500 tests 918 EUR
Description: 3.9 is an anti-human monoclonal antibody that forms an immune complex with the CD11c antigen.

XFD647 Anti-human CD16 Antibody *3G8, XFD647 Same Structure to Alexa Fluor™ 647*

10161180-100tests AAT Bioquest 100 tests 245 EUR
Description: The 3G8 monoclonal antibody recognizes human CD16a, a 50 - 65 kD transmembrane protein typically found on the surface of macrophages, natural killer cells, dendritic cells, monocytes and neutrophils.

XFD647 Anti-human CD16 Antibody *3G8, XFD647 Same Structure to Alexa Fluor™ 647*

10161181-500tests AAT Bioquest 500 tests 918 EUR
Description: The 3G8 monoclonal antibody recognizes human CD16a, a 50 - 65 kD transmembrane protein typically found on the surface of macrophages, natural killer cells, dendritic cells, monocytes and neutrophils.

XFD647 Anti-human CD1 Antibody *SN13, XFD647 Same Structure to Alexa Fluor™ 647*

10012170-100tests AAT Bioquest 100 tests 547 EUR
Description: The SN13 monoclonal antibody binds to human CD1b, a transmembrane protein commonly found on the surface of langerhans cells, dendritic cells and Tregs.

XFD647 Anti-human CD1 Antibody *SN13, XFD647 Same Structure to Alexa Fluor™ 647*

10012171-500tests AAT Bioquest 500 tests 2051 EUR
Description: The SN13 monoclonal antibody binds to human CD1b, a transmembrane protein commonly found on the surface of langerhans cells, dendritic cells and Tregs.

XFD647 Anti-human CD1 Antibody *L161, XFD647 Same Structure to Alexa Fluor™ 647*

10013170-100tests AAT Bioquest 100 tests 547 EUR
Description: L161 is an anti-human monoclonal antibody that is specific for the CD1c antigen.

XFD647 Anti-human CD1 Antibody *L161, XFD647 Same Structure to Alexa Fluor™ 647*

10013171-500tests AAT Bioquest 500 tests 2051 EUR
Description: L161 is an anti-human monoclonal antibody that is specific for the CD1c antigen.

XFD647 Anti-human CD72 Antibody *3F3, XFD647 Same Structure to Alexa Fluor™ 647*

10720180-100tests AAT Bioquest 100 tests 547 EUR
Description: The 3F3 monoclonal antibody binds with human CD72, a 39 - 43 kD transmembrane glycoprotein often located on the surface of B cells, dendritic cells, liver kupffer cells and macrophages.

XFD647 Anti-human CD72 Antibody *3F3, XFD647 Same Structure to Alexa Fluor™ 647*

10720181-500tests AAT Bioquest 500 tests 2051 EUR
Description: The 3F3 monoclonal antibody binds with human CD72, a 39 - 43 kD transmembrane glycoprotein often located on the surface of B cells, dendritic cells, liver kupffer cells and macrophages.

XFD647 Anti-human CD73 Antibody *AD2, XFD647 Same Structure to Alexa Fluor™ 647*

10730180-100tests AAT Bioquest 100 tests 547 EUR
Description: AD2 is an anti-human monoclonal antibody that is specific for the CD73 antigen.

XFD647 Anti-human CD73 Antibody *AD2, XFD647 Same Structure to Alexa Fluor™ 647*

10730181-500tests AAT Bioquest 500 tests 2051 EUR
Description: AD2 is an anti-human monoclonal antibody that is specific for the CD73 antigen.

XFD647 Anti-human CD32 Antibody *3D3, XFD647 Same Structure to Alexa Fluor™ 647*

10321180-100tests AAT Bioquest 100 tests 547 EUR
Description: The 3D3 monoclonal antibody binds to human CD32, a 40 kD member of the Ig superfamily often located on the surface of platelets, monocytes, B cells, granulocytes and dendritic cells.

XFD647 Anti-human CD32 Antibody *3D3, XFD647 Same Structure to Alexa Fluor™ 647*

10321181-500tests AAT Bioquest 500 tests 2051 EUR
Description: The 3D3 monoclonal antibody binds to human CD32, a 40 kD member of the Ig superfamily often located on the surface of platelets, monocytes, B cells, granulocytes and dendritic cells.

XFD647 Anti-human CD19 Antibody *4G7, XFD647 Same Structure to Alexa Fluor™ 647*

10193180-100tests AAT Bioquest 100 tests 245 EUR
Description: The 4G7 monoclonal antibody binds with human CD19, a 95 kD transmembrane protein commonly expressed on the surface of B cells and lymphocytes.

XFD647 Anti-human CD19 Antibody *4G7, XFD647 Same Structure to Alexa Fluor™ 647*

10193181-500tests AAT Bioquest 500 tests 918 EUR
Description: The 4G7 monoclonal antibody binds with human CD19, a 95 kD transmembrane protein commonly expressed on the surface of B cells and lymphocytes.

XFD647 Anti-mouse CD19 Antibody *1D3, XFD647 Same Structure to Alexa Fluor™ 647*

10194170-100tests AAT Bioquest 100 tests 245 EUR
Description: 1D3 is an anti-mouse monoclonal antibody that is specific for the CD19 antigen.

XFD647 Anti-mouse CD19 Antibody *1D3, XFD647 Same Structure to Alexa Fluor™ 647*

10194171-500tests AAT Bioquest 500 tests 918 EUR
Description: 1D3 is an anti-mouse monoclonal antibody that is specific for the CD19 antigen.

XFD647 Anti-human CD38 Antibody *HB7, XFD647 Same Structure to Alexa Fluor™ 647*

10382170-100tests AAT Bioquest 100 tests 245 EUR
Description: HB7 is an anti-human monoclonal antibody that recognizes the CD38 antigen.

XFD647 Anti-human CD38 Antibody *HB7, XFD647 Same Structure to Alexa Fluor™ 647*

10382171-500tests AAT Bioquest 500 tests 918 EUR
Description: HB7 is an anti-human monoclonal antibody that recognizes the CD38 antigen.

XFD647 Anti-human CD40 Antibody *G28.5, XFD647 Same Structure to Alexa Fluor™ 647*

10401180-100tests AAT Bioquest 100 tests 245 EUR
Description: G28.5 is an anti-human monoclonal antibody that targets the CD40 antigen.

XFD647 Anti-human CD40 Antibody *G28.5, XFD647 Same Structure to Alexa Fluor™ 647*

10401181-500tests AAT Bioquest 500 tests 918 EUR
Description: G28.5 is an anti-human monoclonal antibody that targets the CD40 antigen.

XFD647 Anti-human CD45 Antibody *2D1, XFD647 Same Structure to Alexa Fluor™ 647*

10454180-100tests AAT Bioquest 100 tests 245 EUR
Description: 2D1 is an anti-human monoclonal antibody that recognizes the CD45 antigen.

XFD647 Anti-human CD45 Antibody *2D1, XFD647 Same Structure to Alexa Fluor™ 647*

10454181-500tests AAT Bioquest 500 tests 918 EUR
Description: 2D1 is an anti-human monoclonal antibody that recognizes the CD45 antigen.

XFD647 Anti-human CD82 Antibody *C33, XFD647 Same Structure to Alexa Fluor™ 647*

10820180-100tests AAT Bioquest 100 tests 547 EUR
Description: The C33 monoclonal antibody binds with human CD82, a 45 - 90 kD member of the 4-span transmembrane protein superfamily often located on the surface of epithelial cells, fibroblasts, endothelial cells and lymphocytes.

XFD647 Anti-human CD82 Antibody *C33, XFD647 Same Structure to Alexa Fluor™ 647*

10820181-500tests AAT Bioquest 500 tests 2051 EUR
Description: The C33 monoclonal antibody binds with human CD82, a 45 - 90 kD member of the 4-span transmembrane protein superfamily often located on the surface of epithelial cells, fibroblasts, endothelial cells and lymphocytes.

XFD647 Anti-human CD111 Antibody *R1.302, XFD647 Same Structure to Alexa Fluor™ 647*

11110170-100tests AAT Bioquest 100 tests 547 EUR
Description: R1.302 is an anti-human monoclonal antibody that forms an immune complex with the CD111 antigen.

XFD647 Anti-human CD111 Antibody *R1.302, XFD647 Same Structure to Alexa Fluor™ 647*

11110171-500tests AAT Bioquest 500 tests 2051 EUR
Description: R1.302 is an anti-human monoclonal antibody that forms an immune complex with the CD111 antigen.

XFD647 Anti-human CD112 Antibody *R2.525, XFD647 Same Structure to Alexa Fluor™ 647*

11120170-100tests AAT Bioquest 100 tests 547 EUR
Description: R2.525 is an anti-human monoclonal antibody that forms an immune complex with the CD112 antigen.

XFD647 Anti-human CD112 Antibody *R2.525, XFD647 Same Structure to Alexa Fluor™ 647*

11120171-500tests AAT Bioquest 500 tests 2051 EUR
Description: R2.525 is an anti-human monoclonal antibody that forms an immune complex with the CD112 antigen.

XFD647 Anti-human CD3 Antibody *HIT3a, XFD647 Same Structure to Alexa Fluor™ 647*

10030180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD3 Antibody *HIT3a, XFD647 Same Structure to Alexa Fluor™ 647*

10030181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD3 Antibody *HIT3b, XFD647 Same Structure to Alexa Fluor™ 647*

10031180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD3 Antibody *HIT3b, XFD647 Same Structure to Alexa Fluor™ 647*

10031181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD3 Antibody *UCHT1, XFD647 Same Structure to Alexa Fluor™ 647*

10032180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD3 Antibody *UCHT1, XFD647 Same Structure to Alexa Fluor™ 647*

10032181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD4 Antibody *HIT4a, XFD647 Same Structure to Alexa Fluor™ 647*

10040180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD4 Antibody *HIT4a, XFD647 Same Structure to Alexa Fluor™ 647*

10040181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD5 Antibody *HISM2, XFD647 Same Structure to Alexa Fluor™ 647*

10050180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD5 Antibody *HISM2, XFD647 Same Structure to Alexa Fluor™ 647*

10050181 AAT Bioquest 500 tests 918 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD5 Antibody *L17F12, XFD647 Same Structure to Alexa Fluor™ 647*

10051180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

XFD647 Anti-human CD13 Antibody *WM15, XFD647 Same Structure to Alexa Fluor™ 647*

10130180 AAT Bioquest 100 tests 245 EUR
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn
The Xc TALome reveals a number of indicators of DNA rearrangements that most likely drove its evolution from two ancestral tal genes. We found that Tal12a and Tal15a of Xcc pressure Xca5 contribute collectively in the event of illness signs on vulnerable B. oleracea var. botrytis cv Clovis. This giant and polymorphic repertoire of TALEs opens novel views for elucidating TALE-mediated susceptibility of Brassicaceae to black rot illness and for understanding the molecular processes underlying TALE evolution.

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