Listeria

Structural insights into the specific recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL effectors.

Structural insights into the specific recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL effectors.

Transcription activator-like effectors (TALEs) acknowledge DNA by means of repeat-variable diresidues (RVDs) and TALE-DNA interactions are delicate to DNA modifications. Our earlier research deciphered the recognition of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) by TALEs. Here, we report seven crystal buildings of TALE-DNA complexes. The 5mC-specific RVD HA acknowledges 5mC by means of van der Waals …

Structural insights into the specific recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL effectors. Read More »

SWEET genes and TAL effectors for disease resistance in plants: Present status and future prospects

SWEET genes and TAL effectors for disease resistance in plants: Present status and future prospects

SWEET genes encode sugar transporter proteins and usually perform as susceptibility (S) genes. Consequently, the recessive alleles of those SWEET genes present resistance. This evaluate summarizes the accessible literature on the molecular foundation of the position of SWEET genes (as S genes) in the host and corresponding transcription activator-like effectors (TALEs) secreted by the pathogen. …

SWEET genes and TAL effectors for disease resistance in plants: Present status and future prospects Read More »